| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.370 | AlteredExpression | group | BEFREE | In this study, we found that the patients of both myelodysplastic syndromes and chronic myeloid leukaemia with BMI1 overexpression had a higher risk in malignant myeloid progression. | 24571310 | 2014 | ||||
|
0.370 | Biomarker | group | CTD_human | In this study, we found that the patients of both myelodysplastic syndromes and chronic myeloid leukaemia with BMI1 overexpression had a higher risk in malignant myeloid progression. | 24571310 | 2014 | ||||
|
0.370 | Biomarker | group | BEFREE | This expression pattern was similar to that of Bmi-1, an important marker in predicting MDS/AML progression. | 24283704 | 2013 | ||||
|
0.370 | GeneticVariation | group | BEFREE | Our results indicate that BMI1 overexpression is one of the second hit partner genes of RUNX1 mutations that contribute to the development of MDSs. | 23471304 | 2013 | ||||
|
0.370 | AlteredExpression | group | BEFREE | Collectively, overexpression of BMI1 induces resistance to apoptosis and contributes to adverse prognosis in MDS. | 22120066 | 2012 | ||||
|
0.370 | GeneticVariation | group | BEFREE | Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring. | 21125401 | 2011 | ||||
|
0.370 | AlteredExpression | group | BEFREE | We have reported that the expression of BMI1, a member of PcG, in hematopoietic stem cells or progenitor cells predicts the prognosis of patients with MDS and progression to acute leukemia. | 18000383 | 2007 | ||||
|
0.370 | AlteredExpression | group | BEFREE | Furthermore, Bmi-1 expression is up-regulated in transgenic mice that constitutively overexpress human SALL4, and the levels of Bmi-1 in these mice increase as they progress from normal to preleukemic (myelodysplastic syndrome) and leukemic (acute myeloid leukemia) stages. | 17557835 | 2007 |