Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 28309
Gene Symbol: IGHV3OR16-7
IGHV3OR16-7
0.050 AlteredExpression disease BEFREE A high expression of CD49d (>30%) was found in 142/415 (34%) patients and was associated with progressive disease (advanced clinical stage, high serum lactate dehydrogenase or β2 -microglobulin levels; all p < 0·05) and aggressive disease biology (increased ZAP70 or CD38, unmutated IGHV, trisomy 12, mutations of NOTCH1 and SF3B1; all P < 0·05). 26559905 2016
Entrez Id: 28309
Gene Symbol: IGHV3OR16-7
IGHV3OR16-7
0.050 GeneticVariation disease BEFREE Longitudinal copy number, whole exome and targeted deep sequencing of 'good risk' IGHV-mutated CLL patients with progressive disease. 26847028 2016
Entrez Id: 28309
Gene Symbol: IGHV3OR16-7
IGHV3OR16-7
0.050 GeneticVariation disease BEFREE We investigated the molecular characteristics of 19 SDRPL patients, 5 of them with progressive disease.IGHV genes were mutated in 9/13 (69%). 26426381 2016
Entrez Id: 28309
Gene Symbol: IGHV3OR16-7
IGHV3OR16-7
0.050 GeneticVariation disease BEFREE Strikingly, it was also associated with progressive disease within the mutated IGHV gene subset. 22160382 2012
Entrez Id: 28309
Gene Symbol: IGHV3OR16-7
IGHV3OR16-7
0.050 Biomarker disease BEFREE CLL is subdivided into two disease subtypes, whereby leukemias with hypermutated immunoglobulin heavy chain variable (IGHV) genes have a more favorable prognosis than those with unmutated IGHV genes, which tend to show advanced, progressive disease, adverse cytogenetic features and resistance to therapy. 22591389 2012