Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.500 Therapeutic disease RGD Ellagic Acid Prevents Oxidative Stress, Inflammation, and Histopathological Alterations in Acrylamide-Induced Hepatotoxicity in Wistar Rats. 31342809 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.500 Therapeutic disease RGD Ellagic Acid Prevents Oxidative Stress, Inflammation, and Histopathological Alterations in Acrylamide-Induced Hepatotoxicity in Wistar Rats. 31342809 2019
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.500 ModifyingMutation disease RGD Dysregulation of BSEP and MRP2 May Play an Important Role in Isoniazid-Induced Liver Injury via the SIRT1/FXR Pathway in Rats and HepG2 Cells. 30068870 2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.500 Therapeutic disease RGD Acetyl-l-carnitine attenuates arsenic-induced liver injury by abrogation of mitochondrial dysfunction, inflammation, and apoptosis in rats. 29278859 2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		0.500 Biomarker disease CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043 2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		0.500 Therapeutic disease RGD Date fruits inhibit hepatocyte apoptosis and modulate the expression of hepatocyte growth factor, cytochrome P450 2E1 and heme oxygenase-1 in carbon tetrachloride-induced liver fibrosis. 27960551 2017
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.500 Biomarker disease RGD Dose-related liver injury of Geniposide associated with the alteration in bile acid synthesis and transportation. 28827769 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.500 Therapeutic disease CTD_human Prediction of drug-induced liver injury using keratinocytes. 28138970 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.500 Biomarker disease CTD_human Prediction of drug-induced liver injury using keratinocytes. 28138970 2017
Entrez Id: 7450
Gene Symbol: VWF
VWF 		0.500 Biomarker disease CTD_human Von Willebrand factor deficiency reduces liver fibrosis in mice. 28527913 2017
Entrez Id: 2936
Gene Symbol: GSR
GSR 		0.500 Biomarker disease CTD_human Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models. 28069987 2017
Entrez Id: 2875
Gene Symbol: GPT
GPT 		0.500 Therapeutic disease RGD GC-MS Analysis: In Vivo Hepatoprotective and Antioxidant Activities of the Essential Oil of Achillea biebersteinii Afan. Growing in Saudi Arabia. 27293452 2016
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		0.500 Biomarker disease RGD Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment. 27324775 2016
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.500 Biomarker disease CTD_mouse Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. 26134275 2015
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		0.500 Biomarker disease CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249 2015
Entrez Id: 761
Gene Symbol: CA3
CA3 		0.500 Biomarker disease CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249 2015
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.500 Biomarker disease CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249 2015
Entrez Id: 2936
Gene Symbol: GSR
GSR 		0.500 Therapeutic disease RGD Beneficial effects of Chrysin against Methotrexate-induced hepatotoxicity via attenuation of oxidative stress and apoptosis. 24154663 2014
Entrez Id: 761
Gene Symbol: CA3
CA3 		0.500 Biomarker disease CTD_mouse Characterization of chemically induced liver injuries using gene co-expression modules. 25226513 2014
Entrez Id: 2936
Gene Symbol: GSR
GSR 		0.500 Biomarker disease CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513 2014
Entrez Id: 5428
Gene Symbol: POLG
POLG 		0.500 SusceptibilityMutation disease RGD Acute liver failure after valproate exposure in patients with POLG1 mutations and the prognosis after liver transplantation. 25065347 2014
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.500 Therapeutic disease RGD The protection by heme oxygenase-1 induction against thioacetamide-induced liver toxicity is associated with changes in arginine and asymmetric dimethylarginine. 22886620 2013
Entrez Id: 2936
Gene Symbol: GSR
GSR 		0.500 Biomarker disease RGD Expression of Glutathione Peroxidase and Glutathione Reductase and Level of Free Radical Processes under Toxic Hepatitis in Rats. 23554813 2013
Entrez Id: 350
Gene Symbol: APOH
APOH 		0.500 Biomarker disease RGD Identification of novel liver-specific mRNAs in plasma for biomarkers of drug-induced liver injury and quantitative evaluation in rats treated with various hepatotoxic compounds. 23288050 2013
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.500 Therapeutic disease CTD_human Urinary excretion of bilirubin oxidative metabolites in arsenite-treated mice. 22688006 2012