Associated Disease N. genes N. variants N. of shared genes JI g p-value g N. of shared variants JI v p-value v
CUI: C0037772
Disease: Spastic Paraplegia
Spastic Paraplegia
144 93 67 0.34 8 6.3E-02
CUI: C0034152
Disease: Henoch-Schoenlein Purpura
Henoch-Schoenlein Purpura
198 59 71 0.28 3 3.1E-02
CUI: C0231687
Disease: Spastic gait
Spastic gait
62 0 38 0.26 0 0
CUI: C0034935
Disease: Babinski Reflex
Babinski Reflex
218 0 67 0.24 0 0
CUI: C0037771
Disease: Paraparesis, Spastic
Paraparesis, Spastic
75 37 33 0.20 3 4.0E-02
CUI: C1836296
Disease: Muscle Weakness Lower Limb
Muscle Weakness Lower Limb
74 0 32 0.19 0 0
CUI: C1271100
Disease: Lower limb spasticity
Lower limb spasticity
43 5 25 0.18 1 2.2E-02
Hereditary Autosomal Dominant Spastic Paraplegia
27 7 19 0.15 1 2.1E-02
Autosomal Recessive Hereditary Spastic Paraplegia
20 0 18 0.14 0 0
Urinary bladder sphincter dysfunction
28 0 19 0.14 0 0
CUI: C0238651
Disease: Ankle clonus
Ankle clonus
32 5 18 0.13 1 2.2E-02
CUI: C0039273
Disease: Talipes cavus
Talipes cavus
213 0 39 0.13 0 0
CUI: C1836696
Disease: Lower limb hyperreflexia
Lower limb hyperreflexia
38 0 18 0.13 0 0
Impaired vibration sensation in the lower limbs
39 0 18 0.12 0 0
CUI: C1848736
Disease: Distal amyotrophy
Distal amyotrophy
106 0 24 0.12 0 0
CUI: C1263857
Disease: Peripheral axonal neuropathy
Peripheral axonal neuropathy
94 0 22 0.11 0 0
Complicated hereditary spastic paraplegia
16 0 14 0.11 0 0
CUI: C1849156
Disease: Spastic Ataxia
Spastic Ataxia
28 3 15 0.11 1 2.3E-02
CUI: C0085606
Disease: Urgency of micturition
Urgency of micturition
40 0 16 0.11 0 0
CUI: C0311394
Disease: Difficulty walking
Difficulty walking
224 30 33 0.11 1 1.4E-02
CUI: C1854494
Disease: Slow progression
Slow progression
165 0 27 0.10 0 0
CUI: C1855483
Disease: Progressive spastic paraplegia
Progressive spastic paraplegia
59 0 17 0.10 0 0
CUI: C0454596
Disease: Dysarthria, Spastic
Dysarthria, Spastic
30 0 14 0.10 0 0
CUI: C4553976
Disease: Urinary Urgency, CTCAE 5
Urinary Urgency, CTCAE 5
34 0 14 9.8E-02 0 0
CUI: C0151889
Disease: Hyperreflexia
Hyperreflexia
539 0 58 9.6E-02 0 0