Source: CLINVAR ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
CASP10 Q92851 caspase 10 Enzyme 4.6E-12 0.528 0.692
KLF6 Q99612 Kruppel like factor 6 Nucleic acid binding 0.98 0.501 0.846
IRF1 P10914 interferon regulatory factor 1 Transcription factor 0.99 0.468 0.769