Disease: Memory Loss
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
INS P01308 insulin 0.30 0.445 0.923
ITM2B Q9Y287 integral membrane protein 2B 0.63 0.617 0.654
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LEP P41159 leptin 0.46 0.349 0.846
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885