Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ABCA7 | Q8IZY2 | ATP binding cassette subfamily A member 7 | Transporter | 2.1E-55 | 0.644 | 0.577 |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
ADAM10 | O14672 | ADAM metallopeptidase domain 10 | 1.00 | 0.489 | 0.846 | |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
CR1 | P17927 | complement C3b/C4b receptor 1 (Knops blood group) | 1.6E-35 | 0.533 | 0.808 | |
CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
CTSB | P07858 | cathepsin B | Enzyme | 5.9E-11 | 0.457 | 0.846 |
CTSD | P07339 | cathepsin D | Enzyme | 9.2E-04 | 0.478 | 0.846 |
CYP46A1 | Q9Y6A2 | cytochrome P450 family 46 subfamily A member 1 | Enzyme | 0.99 | 0.659 | 0.500 |
ENO2 | P09104 | enolase 2 | Enzyme | 0.38 | 0.475 | 0.846 |
FANCD2 | Q9BXW9 | FA complementation group D2 | 1.1E-30 | 0.479 | 0.885 | |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
ITM2B | Q9Y287 | integral membrane protein 2B | 0.63 | 0.617 | 0.654 | |
LRP8 | Q14114 | LDL receptor related protein 8 | 1.00 | 0.644 | 0.346 | |
MAOB | P27338 | monoamine oxidase B | 1.00 | 0.533 | 0.808 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
MME | P08473 | membrane metalloendopeptidase | Enzyme | 1.5E-18 | 0.407 | 0.808 |