Disease: Mental deficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADRA2B P18089 adrenoceptor alpha 2B G-protein coupled receptor 4.5E-06 0.465 0.846
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CACNA1G O43497 calcium voltage-gated channel subunit alpha1 G Ion channel 1.00 0.590 0.577
CHD2 O14647 chromodomain helicase DNA binding protein 2 1.00 0.585 0.577
CHD8 Q9HCK8 chromodomain helicase DNA binding protein 8 1.00 0.656 0.577
CIC Q96RK0 capicua transcriptional repressor 1.00 0.523 0.692
DEAF1 O75398 DEAF1 transcription factor 3.4E-04 0.575 0.615
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
FOLR1 P15328 folate receptor alpha 0.13 0.522 0.885
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
FRAXE fragile site, folic acid type, rare, fra(X)(q28) E 0.636 0.462
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
HDAC4 P56524 histone deacetylase 4 Epigenetic regulator 1.00 0.484 0.885
KDM5A P29375 lysine demethylase 5A 1.00 0.597 0.731
KDM5C P41229 lysine demethylase 5C 1.00 0.581 0.538
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
MCPH1 Q8NEM0 microcephalin 1 Nucleic acid binding 7.8E-30 0.540 0.846
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MEF2C Q06413 myocyte enhancer factor 2C Transcription factor 1.7E-02 0.517 0.769
NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit Enzyme 1.00 0.700 0.423