rs116855232
|
|
|
0.750 |
GeneticVariation |
GWASCAT |
We confirmed the association of NUDT15 p.Arg139Cys with leukopenia and alopecia (p = 2.20E-63, 1.32E-69, OR = 6.59, 12.1, respectively), and found a novel association with digestive symptoms (p = 6.39E-04, OR = 1.89).
|
29923122 |
2018 |
rs116855232
|
|
|
0.750 |
GeneticVariation |
BEFREE |
We confirmed the association of NUDT15 p.Arg139Cys with leukopenia and alopecia (p = 2.20E-63, 1.32E-69, OR = 6.59, 12.1, respectively), and found a novel association with digestive symptoms (p = 6.39E-04, OR = 1.89).
|
29923122 |
2018 |
rs116855232
|
|
|
0.750 |
GeneticVariation |
BEFREE |
Therefore, the NUDT15 p.R139C variant is common and strongly associated with AZA-induced early leukopenia and severe alopecia in Korean patients with various neurological diseases.
|
28566182 |
2017 |
rs116855232
|
|
|
0.750 |
GeneticVariation |
BEFREE |
NUDT15 R139C (rs116855232) is a recently identified genetic factor responsible for thiopurine-induced leukocytopenia and hair loss.
|
26590936 |
2016 |
rs116855232
|
|
|
0.750 |
GeneticVariation |
BEFREE |
Extensive hair loss was a recognizable early symptom in patients with the homozygous NUDT15 c.415C>T variant.
|
26735160 |
2016 |
rs116855232
|
|
|
0.750 |
GeneticVariation |
BEFREE |
NUDT R139C was significantly associated with early severe hair loss in Japanese patients with IBD.
|
26076924 |
2016 |
rs9282858
|
|
T |
0.710 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs9282858
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Our study provides evidence that the SRD5A2 A49T A variant is associated with an increased risk of prostate cancer, lower levels of circulating 3alpha-diolG and decreased risk of baldness.
|
17136762 |
2007 |
rs117927258
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
|
29923122 |
2018 |
rs145080284
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
|
29923122 |
2018 |
rs75466870
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
|
29923122 |
2018 |
rs78844412
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
|
29923122 |
2018 |
rs1005734
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10193725
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10225279
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10278449
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10502861
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10516537
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10771462
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10808813
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs1081073
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10843003
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10888690
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10903128
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |
rs10919382
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genetic prediction of male pattern baldness.
|
28196072 |
2017 |