<i>GSTP1</i> rs1695 showed the smallest p value for hematotoxicity association, and the <sup>105</sup>Ile wild type allele had a significantly higher risk of severe hematotoxicity (neutropenia G4, thrombocytopenia ≥ G3 and anemia ≥ G3) than the <sup>105</sup>Val allele (p=0.00034, odds ratio=5.71 (95% confidence interval:1.77-18.44)).
In single-locus analysis, Ile/Val and Ile/Val+Val/Val genotypes of the GSTP1 Ile105Val (rs1695) polymorphism reached statistical significance with grade 2-4 anemia (P=0.019, P=0.027).