Gene: IFNG ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2430561
rs2430561
IFNG ; IFNG-AS1
0.020 GeneticVariation BEFREE The A allele of rs2430561 in IFN<i>γ</i> was indicative for severe periodontitis among the patients with rheumatoid arthritis (<i>p</i> = 0.039). 30890897

2019
dbSNP: rs2430561
rs2430561
IFNG ; IFNG-AS1
0.020 GeneticVariation BEFREE Our results do not support a role of IFNG rs2430561 (+874T/A) functional gene variant in the development of CV disease in RA patients. 23077565

2012
dbSNP: rs2069705
rs2069705
IFNG ; IFNG-AS1
0.010 GeneticVariation BEFREE Finally, we verified higher IL-6 value in the RA patients than healthy control group (p = 0.007) and an association between high IL-6 levels and increased CDAI (r = 0.4648, p = 0.0015); DAS 28 (r = 0.3933, p= 0.0091), presence of bone erosions (r = 0.3170, p = 0.0361), ESR levels(r = 0.3041, p = 0.0448) and IFN-γ levels (r = 0.3049, p = 0.0468).Altogether, we suggest that IL10 -1082 (T>C, rs1800896) and INFG -1616(A>G, rs2069705) polymorphisms as well as IL-6 levels alterations may play a role for prognostic and disease follow-up. 31494241

2020