| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.030 | GeneticVariation | BEFREE | Published data on the association between <i>MMP-9</i> polymorphisms (-1562 C > T, rs3918242; Gln279Arg, rs17576 Arg668Gln, rs17577) and asthma susceptibility are inconclusive. | 30931075 | 2019 |
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0.030 | GeneticVariation | BEFREE | MMP-9 -1562C>T and 836G>A (Arg279Gln) were not associated with asthma (p> or =0.15) or asthma severity (p> or =0.13), and TIMP-1 434T>C (Phe124Phe) was not associated with asthma in women (p = 0.094) or men (p = 0.207). | 16061701 | 2005 |
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|
0.030 | GeneticVariation | BEFREE | We were interested in whether the polymorphisms -T1702A, -C1562T, R279Q and +C6T within the matrix metalloproteinase 9 (MMP-9) gene were associated with asthma in a population of 231 asthmatic children.However, we found no association. | 16026590 | 2005 |
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|
0.020 | GeneticVariation | BEFREE | The present meta-analysis suggests that <i>MMP-9</i> Arg668Gln, rs17577 polymorphism may be the risk factor for asthma susceptibility. | 30931075 | 2019 |
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|
0.020 | GeneticVariation | BEFREE | We found that the SNPs rs2274755, rs17577, and rs3918249 were associated with asthma risk. | 23639553 | 2013 |
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|
0.010 | GeneticVariation | BEFREE | Overall, we found no significant association between -1562 C > T, rs3918242 polymorphism, and asthma susceptibility in any of the genetic model comparisons. | 30931075 | 2019 |
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|
0.010 | GeneticVariation | BEFREE | The main finding of our study is the association of MMP9 genotypes rs20544 TT and rs13925 AA and AG with better asthma control, and indirectly better response to treatment. | 29600353 | 2018 |
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0.010 | GeneticVariation | BEFREE | The main finding of our study is the association of MMP9 genotypes rs20544 TT and rs13925 AA and AG with better asthma control, and indirectly better response to treatment. | 29600353 | 2018 |
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|
0.010 | GeneticVariation | BEFREE | The SNP rs3918249 exhibited a female gender-dependent association with asthma (OR=1.66, 95% CI 1.14-2.43, P=0.007). | 23639553 | 2013 |