|
rs710521
|
|
A |
0.740 |
GeneticVariation |
GWASDB |
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
|
20972438 |
2010 |
|
rs710521
|
|
A |
0.740 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
|
24163127 |
2014 |
|
rs710521
|
|
|
0.740 |
GeneticVariation |
BEFREE |
We genotyped rs9642880 G>T on 8q24 and rs710521</span> A>G on 3q28 in a two-stage case-control study of bladder cancer to evaluate the association and further examined the expression of MYC.
|
19369583 |
2009 |
|
rs710521
|
|
A |
0.740 |
GeneticVariation |
GWASDB |
Sequence variant on 8q24 confers susceptibility to urinary bladder cancer.
|
18794855 |
2008 |
|
rs710521
|
|
A |
0.740 |
GeneticVariation |
GWASDB |
A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.
|
20348956 |
2010 |
|
rs710521
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Performing a meta-analysis of 5,695 cases and 40,187 controls including all published studies on rs710521, a convincing association with bladder cancer risk was obtained (OR = 1.18; 95% Cl = 1.12-1.25; P < 0.0001).
|
21063684 |
2010 |
|
rs710521
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Fine-mapping of the GWAS signal region led to the identification of twenty SNPs that showed a stronger association with bladder cancer risk than rs710521.
|
29956121 |
2018 |
|
rs710521
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Genome-wide association studies have confirmed association of TP63C/T rs710521, TERTC/T rs2736098, and SLC14A1C/T rs17674580 gene variants with susceptibility to bladder cancer (BC) in European and White population.
|
25218484 |
2014 |
|
rs1014971
|
|
|
0.720 |
GeneticVariation |
BEFREE |
In a combined analysis, we identified three new regions associated with bladder cancer on chromosomes 22q13.1, 19q12 and 2q37.1: rs1014971, (P = 8 × 10⁻¹²) maps to a non-genic region of chromosome 22q13.1, rs8102137 (P = 2 × 10⁻¹¹) on 19q12 maps to CCNE1 and rs11892031 (P = 1 × 10⁻⁷) maps to the UGT1A cluster on 2q37.1.
|
20972438 |
2010 |
|
rs1014971
|
|
T |
0.720 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
|
24163127 |
2014 |
|
rs1014971
|
|
|
0.720 |
GeneticVariation |
BEFREE |
SNP rs1014971 was associated with bladder cancer risk, increased APOBEC3B expression, and enrichment with APOBEC-signature mutations in bladder tumors.
|
27643540 |
2016 |
|
rs1014971
|
|
|
0.720 |
GeneticVariation |
GWASDB |
In a combined analysis, we identified three new regions associated with bladder cancer on chromosomes 22q13.1, 19q12 and 2q37.1: rs1014971, (P = 8 × 10⁻¹²) maps to a non-genic region of chromosome 22q13.1, rs8102137 (P = 2 × 10⁻¹¹) on 19q12 maps to CCNE1 and rs11892031 (P = 1 × 10⁻⁷) maps to the UGT1A cluster on 2q37.1.
|
20972438 |
2010 |
|
rs1495741
|
|
|
0.720 |
GeneticVariation |
BEFREE |
Overall, seven of the 14 variants were significantly associated with bladder cancer risk (p = 9.763 × 10(-3) for rs9642880 at 8q24.21, p = 3.004 × 10(-3) for rs2294008 at 8q24.3, p = 0.012 for rs798766 at 4p16.3, p = 0.034 for rs1495741 at </span>8p22, p = 2.306 × 10(-4) for GSTM1, p = 8.507 × 10(-8) for rs17674580 at 18q12.3, p = 7.179 × 10(-4) for rs10936599 at 3q26.2) and the odds ratios (ORs) ranged from 1.13 to 1.65.
|
24740636 |
2014 |
|
rs1495741
|
|
|
0.720 |
GeneticVariation |
GWASDB |
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
|
20972438 |
2010 |
|
rs1495741
|
|
A |
0.720 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
|
24163127 |
2014 |
|
rs1495741
|
|
|
0.720 |
GeneticVariation |
BEFREE |
To quantify the association between rs1495741 and the risk of bladder cancer and to estimate the interaction effect of this genetic variant with smoking, we performed a systematic literature review and meta-analysis involving 14,815 cases and 58,282 controls from 29 studies.
|
27495060 |
2016 |
|
rs8102137
|
|
|
0.720 |
GeneticVariation |
BEFREE |
In a combined analysis, we identified three new regions associated with bladder cancer on chromosomes 22q13.1, 19q12 and 2q37.1: rs1014971, (P = 8 × 10⁻¹²) maps to a non-genic region of chromosome 22q13.1, rs8102137 (P = 2 × 10⁻¹¹) on 19q12 maps to CCNE1 and rs11892031 (P = 1 × 10⁻⁷) maps to the UGT1A cluster on 2q37.1.
|
20972438 |
2010 |
|
rs8102137
|
|
C |
0.720 |
GeneticVariation |
GWASDB |
In a combined analysis, we identified three new regions associated with bladder cancer on chromosomes 22q13.1, 19q12 and 2q37.1: rs1014971, (P = 8 × 10⁻¹²) maps to a non-genic region of chromosome 22q13.1, rs8102137 (P = 2 × 10⁻¹¹) on 19q12 maps to CCNE1 and rs11892031 (P = 1 × 10⁻⁷) maps to the UGT1A cluster on 2q37.1.
|
20972438 |
2010 |
|
rs8102137
|
|
C |
0.720 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
|
24163127 |
2014 |
|
rs8102137
|
|
|
0.720 |
GeneticVariation |
BEFREE |
We found that the original GWAS marker rs8102137 represents a group of 47 linked SNPs (with r(2) ≥ 0.7) associated with increased bladder cancer risk.
|
25320178 |
2014 |
|
rs62185668
|
|
A |
0.710 |
GeneticVariation |
GWASDB |
Several correlated variants at 20p12, represented by rs62185668, show genome-wide significant association with UBC after combining discovery and replication results (OR = 1.19, P = 1.5 × 10(-11) for rs62185668-A, minor allele frequency = 23.6%).
|
24861552 |
2014 |
|
rs62185668
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Several correlated variants at 20p12, represented by rs62185668, show genome-wide significant association with UBC after combining discovery and replication results (OR = 1.19, P = 1.5 × 10(-11) for rs62185668-A, minor allele frequency = 23.6%).
|
24861552 |
2014 |
|
rs2204008
|
|
T |
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
|
24163127 |
2014 |
|
rs833052
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Our meta-analysis suggested that rs3025039 (C > T), rs833052 (C > A) and rs25648 (C > T) polymorphisms of VEGF gene increased susceptibility to BCa risk.
|
30849545 |
2019 |
|
rs833052
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The VEGF gene rs3025039C/T and rs833052C/A variants may contribute to the risk of developing BCa, especially in Asian descendants.
|
30609111 |
2019 |