Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs25489
rs25489
0.080 GeneticVariation BEFREE Moreover, in the subgroup analysis by cancer type, we found that XRCC1-rs25489 polymorphism was associated with an increased risk of bladder cancer (BC) in heterozygote model. 28330811

2017

dbSNP: rs25489
rs25489
0.080 GeneticVariation BEFREE This meta-analysis suggested that XRCC1 Arg194Trp and Arg280His polymorphisms were risk factors for increasing bladder cancer in Asian population. 24266849

2013

dbSNP: rs25489
rs25489
0.080 GeneticVariation BEFREE Our meta-analysis results suggest that XRCC1 Arg194Trp and Arg280His polymorphisms are associated with significantly increased risk of bladder cancer in Asians. 23636799

2013

dbSNP: rs25489
rs25489
0.080 GeneticVariation BEFREE However, the XRCC1 R194W and R280H polymorphisms were both associated with increased bladder cancer risk among Asians. 24039945

2013

dbSNP: rs25489
rs25489
0.080 GeneticVariation BEFREE Our meta-analysis shows that XRCC1 Arg194Trp and Arg280His polymorphisms are associated with a significantly increased risk of bladder cancer in Asian population. 23704969

2013

dbSNP: rs25489
rs25489
0.080 GeneticVariation BEFREE We found an increased risk of bladder cancer associated with the XRCC1 194Trp/Trp and 280Arg/His genotypes (adjusted odds ratio = 3.90, 95% confidence interval = 1.69-8.98 for 194Trp/Trp and 2.53, 1.67-3.83 for 280Arg/His) compared with the 194Arg/Arg and 280Arg/Arg genotypes, respectively. 20218899

2010

dbSNP: rs25489
rs25489
0.080 GeneticVariation BEFREE No association was found between the polymorphisms in XRCC1 (Arg(194)Trp, Arg(280)His, Arg(399)Gln) and bladder cancer susceptibility. 18336890

2008

dbSNP: rs25489
rs25489
0.080 GeneticVariation BEFREE We provide no evidence of an association between polymorphisms in XRCC1 and bladder cancer risk, although our study had only limited power to detect the association for low frequency variants, such as Arg280His. 17425776

2007