rs701848
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Moreover, the SNP rs701848 CC, TC genotype showed significantly increased the overall cancer risk both in dominant model [CC/TC vs. TT: OR(95% CI) = 1.25(1.15, 1.36)] and recessive model [CC vs.
|
29259266 |
2017 |
rs701848
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This meta-analysis indicates that the <i>PTEN</i> rs701848 (CC) and rs2735343 (GG) polymorphisms are associated with increased cancer risk in Asian subjects.
|
29221206 |
2017 |
rs701848
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Epidemiologic studies suggested that mutations of the PI3K/PTEN/AKT pathway genes are associated with cancer risk, yet no data are available for PTEN rs701848, PIK3CA rs2699887, and AKT1 rs2494752 polymorphism and breast cancer(BC) risk.
|
28423632 |
2017 |
rs3830675
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Impact of PTEN IVS4 Polymorphism (rs3830675) on Cancer Susceptibility: An Updated Meta-analysis.
|
26417029 |
2016 |
rs3830675
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association of the PTEN IVS4 (rs3830675) gene polymorphism with reduced risk of cancer: evidence from a meta-analysis.
|
25735379 |
2015 |
rs3830675
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The recessive effect model and dominant effect model also demonstrated significant association between PTEN IVS4 (rs3830675) polymorphism and increased cancer risk especially for digestive tract cancer.
|
24901890 |
2014 |
rs121909235
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To our knowledge, this is the first report of PDAC associated with a germline PTEN mutation, particularly a rare variant (p.Arg234Gln</span>) with cancer risks.
|
28755079 |
2018 |
rs2735343
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This meta-analysis indicates that the <i>PTEN</i> rs701848 (CC) and rs2735343 (GG) polymorphisms are associated with increased cancer risk in Asian subjects.
|
29221206 |
2017 |
rs121909224
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We used whole exome sequencing to examine the mutation profiles of the LMD tumor DNA in CSF before therapeutic response and after disease relapse, and discovered a canonical cancer mutation PTEN (R130*) at both time points.
|
26961773 |
2016 |
rs779530981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This combination treatment ultimately leads to the expansion of cancer progenitors with a PTEN E91D mutation, suggesting that the analysis of PTEN mutations could predict therapeutic response to the dual therapy.
|
21138868 |
2010 |
rs1029342144
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Statistically significant associations were noted between SNPs in beta-catenin and APOE and a positive family history of cancer (beta-catenin: p=0.034, APOE: p=0.033); tumor location and a DCC SNP (p=0.038) and the P53 R72P mutation and survival (p=0.0336).
|
15523694 |
2005 |