|
rs10049390
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
|
rs1011970
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
|
27197191 |
2016 |
|
rs10152518
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
|
31089142 |
2019 |
|
rs1017621656
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We now show that stable expression of oncogenic Ki-ras(G12V) c</span>onverts the HD6-4 colon cancer cell line from insensitive to TGF-beta1 to growth-promoted by TGF-beta1.
|
11029459 |
2001 |
|
rs1021631442
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer.
|
23047549 |
2012 |
|
rs10222633
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis within linkage blocks of CASR revealed the G-G-G-G-G-A-C haplotype (rs10222633-rs10934578-rs3804592-rs17250717-A986S-R990G-rs1802757) to be associated with a decreased OS of colon cancer (HR, 3.15; 95% CI, 1.66-5.96).
|
28765616 |
2017 |
|
rs1028166
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk.
|
25192705 |
2014 |
|
rs1035209
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Novel Common Genetic Susceptibility Loci for Colorectal Cancer.
|
29917119 |
2019 |
|
rs1035209
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.
|
24737748 |
2014 |
|
rs1039659576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Neither MTR D919G nor RFC 80G>A polymorphisms were associated with altered colon cancer risk.
|
16284371 |
2005 |
|
rs10411210
|
|
C |
0.710 |
GeneticVariation |
GWASCAT |
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.
|
19011631 |
2008 |
|
rs10411210
|
|
|
0.710 |
GeneticVariation |
BEFREE |
A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PMS2) from 315 families enrolled in the Colon Cancer Family Registry, were genotyped for the single nucleotide polymorphisms (SNPs): rs16892766 (8q23.3), rs6983267 (8q24.21), rs719725 (9p24), rs10795668 (10p14), rs3802842 (11q23.1), rs4444235 (14q22.2), rs4779584 (15q13.3), rs9929218 (16q22.1), rs4939827 (18q21.1), rs10411210 (19q13.1) and rs961253 (20p12.3).
|
23434150 |
2013 |
|
rs10411210
|
|
C |
0.710 |
GeneticVariation |
GWASCAT |
Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.
|
30529582 |
2019 |
|
rs10411210
|
|
C |
0.710 |
GeneticVariation |
GWASCAT |
Novel Common Genetic Susceptibility Loci for Colorectal Cancer.
|
29917119 |
2019 |
|
rs1042522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PIA identified SNPs that may interact with the GSTT1 polymorphism, including coding polymorphisms in TP53 (Arg72Pro in p53) and CASP8 (Asp302His in caspase 8), which may modify the association between this polymorphism and colon cancer.
|
16217767 |
2006 |
|
rs1042636
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis within linkage blocks of CASR revealed the G-G-G-G-G-A-C haplotype (rs10222633-rs10934578-rs3804592-rs17250717-A986S-R990G-rs1802757) to be associated with a decreased OS of colon cancer (HR, 3.15; 95% CI, 1.66-5.96).
|
28765616 |
2017 |
|
rs1042821
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The MSH6 Gly39Glu and MLH1 -93G>A polymorphisms were associated with risk of overall colon and MSI-positive colon cancers, respectively.
|
18523027 |
2009 |
|
rs1042821
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In microsatellite stable tumors, homozygous carriers of the G39E polymorphism had an increased risk of CIMP+ colon cancer (odds ratio (OR) 2.2, 95% confidence interval (CI) 1.1, 4.2) and BRAF V600E mutation (OR 3.1, 95% CI 1.01, 9.7) in a case-control comparison.
|
19582761 |
2009 |
|
rs1044129
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Among seven target variants, rs1044129 at the miR-367 binding site of calcium channel ryanodine receptor gene 3 (RYR3) was associated with relapse-free survival (RFS) for colon cancer patients as a recessive model in a univariate analysis.
|
23393343 |
2013 |
|
rs10450310
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Four SNPs in the 3'-untranslated region (UTR) of the gene (rs10082466, rs2120132, rs2099902, and rs10450310) were associated with an increased risk of colon cancer in African Americans.
|
22282660 |
2012 |
|
rs1045485
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PIA identified SNPs that may interact with the GSTT1 polymorphism, including coding polymorphisms in TP53 (Arg72Pro in p53) and CASP8 (Asp302His in caspase 8), which may modify the association between this polymorphism and colon cancer.
|
16217767 |
2006 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Genetic testing for C3435T MDR1 gene polymorphism may be a suitable test to evaluate the risk for colon cancer in patients under 50 years of age.
|
15912392 |
2005 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The present study suggests that MDR1 2677G>T and 3435C>T polymorphism is not a risk factor for sporadic colon cancer among Bulgarians and that somatic mutation at these sites is not involved in the genesis of colon tumors.
|
17674045 |
2008 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
MDR1 C3435T polymorphism influences the development of colon cancer and adult acute myeloid leukemia by the association with transporting carcinogen.
|
18644389 |
2008 |
|
rs1045642
|
|
|
0.040 |
GeneticVariation |
BEFREE |
G2677T and C3435T polymorphisms are not associated with colon cancer risk and prognosis in a selected patient population.
|
19192650 |
2009 |