|
rs4939827
|
|
T |
0.750 |
GeneticVariation |
GWASCAT |
Novel Common Genetic Susceptibility Loci for Colorectal Cancer.
|
29917119 |
2019 |
|
rs4939827
|
|
T |
0.750 |
GeneticVariation |
GWASCAT |
Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.
|
30529582 |
2019 |
|
rs4939827
|
|
T |
0.750 |
GeneticVariation |
GWASCAT |
Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.
|
26965516 |
2016 |
|
rs4939827
|
|
|
0.750 |
GeneticVariation |
BEFREE |
Both the SMAD7 rs4939827 TT genotype and the CHI3L1 rs4950928 C allele were associated with the rectal but not the colon cancer.
|
26779637 |
2016 |
|
rs4939827
|
|
T |
0.750 |
GeneticVariation |
GWASCAT |
Genome-wide association study of colorectal cancer identifies six new susceptibility loci.
|
26151821 |
2015 |
|
rs4939827
|
|
|
0.750 |
GeneticVariation |
BEFREE |
A total of 927 MMR gene mutation carriers (360 MLH1, 442 MSH2, 85 MSH6 and 40 PMS2) from 315 families enrolled in the Colon Cancer Family Registry, were genotyped for the single nucleotide polymorphisms (SNPs): rs16892766 (8q23.3), rs6983267 (8q24.21), rs719725 (9p24), rs10795668 (10p14), rs3802842 (11q23.1), rs4444235 (14q22.2), rs4779584 (15q13.3), rs9929218 (16q22.1), rs4939827 (18q21.1), rs10411210 (19q13.1) and rs961253 (20p12.3).
|
23434150 |
2013 |
|
rs4939827
|
|
|
0.750 |
GeneticVariation |
GWASCAT |
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
|
23266556 |
2013 |
|
rs4939827
|
|
|
0.750 |
GeneticVariation |
BEFREE |
Rectal tumors were significantly associated with rs4939827 (OR = 4.85, P = 0.002) and rs6983267 (OR = 3.00, P = 0.036), suggesting that carriers of risk alleles at these loci had increased susceptibility to development of rectal cancer rather than colon cancer.
|
22457859 |
2012 |
|
rs4939827
|
|
|
0.750 |
GeneticVariation |
GWASCAT |
Meta-analysis of new genome-wide association studies of colorectal cancer risk.
|
21761138 |
2012 |
|
rs4939827
|
|
|
0.750 |
GeneticVariation |
BEFREE |
The odds ratios between SMAD7 and colon cancer among individuals reporting recent aspirin/nonsteroidal anti-inflammatory drug use was 0.60 (95% CI, 0.43-0.85) for the CC genotype of the rs4939827 polymorphism and 1.69 (95% CI, 1.20-2.38) for the TT genotype of the rs1295371 polymorphism.
|
20124488 |
2010 |
|
rs4939827
|
|
T |
0.750 |
GeneticVariation |
GWASCAT |
Risk was greater for rectal than for colon cancer for rs3802842 (P < 0.008) and rs4939827 (P < 0.009).
|
18372901 |
2008 |
|
rs4939827
|
|
|
0.750 |
GeneticVariation |
BEFREE |
Risk was greater for rectal than for colon cancer for rs3802842 (P < 0.008) and rs4939827 (P < 0.009).
|
18372901 |
2008 |
|
rs4939827
|
|
T |
0.750 |
GeneticVariation |
GWASCAT |
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk.
|
17934461 |
2007 |