rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
APC gene loss of heterozygosity, mutations, E1317Q, and I1307K germ-line variants in sporadic colon cancer in Croatia.
|
15507235 |
2004 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Immunohistochemical analyses of colon cancer in I1307K APC mutation carriers compared with noncarriers.
|
12822869 |
2003 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The I1307K variant was analyzed in 242 eligible respondents who were selected because they had a personal or family history of colon cancer.
|
11159880 |
2001 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The I1307K polymorphism, therefore, exists in all ethnic Jewish populations: Ashkenazi and non-Ashkenazi, with or without colon cancer.
|
11551102 |
2001 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Studies such as those on APC I1307K and CHEK2 1100delC may suggest the way forward for the identification of 'breast-colon cancer' genes.
|
14574178 |
2001 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The reported association between the APC I1307K mutation and colon cancer risk was supported by a correlation in these data between personal or family history of CRC or polyps and a gene mutation.
|
10756345 |
2000 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The I1307K sequence variant was not found in 67 patients with esophageal cancer, 53 patients with gastric carcinoma (13 MSI-H and 44 MSI-negative), or ten patients with sporadic MSI-H colon cancer.
|
10445854 |
1999 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
However, a second study indicated that the I1307K mutation did not contribute greatly to the risk of colon cancer in Ashkenazi breast-ovarian cancer families, and a role of mismatch repair deficiency was suggested.
|
9869603 |
1999 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We have shown that the family's phenotype does not result from APC mutations (including the I1307K variant) or from genetic changes in the other known genes that predispose to colon cancer.
|
10092300 |
1999 |
rs1801155
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Significantly, of the 12 individuals who possessed the I1307K mutation, none was diagnosed with colorectal cancer and none had a known first-, second-, or third-degree relative diagnosed with colon cancer.
|
9407954 |
1997 |
rs1801155
|
|
A |
0.800 |
SusceptibilityMutation |
CLINVAR |
|
|
|
rs755229494
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Discovery of common and rare genetic risk variants for colorectal cancer.
|
30510241 |
2019 |
rs137854575
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs387906234
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
APC gene loss of heterozygosity, mutations, E1317Q, and I1307K germ-line variants in sporadic colon cancer in Croatia.
|
15507235 |
2004 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Immunohistochemical analyses of colon cancer in I1307K APC mutation carriers compared with noncarriers.
|
12822869 |
2003 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The I1307K polymorphism, therefore, exists in all ethnic Jewish populations: Ashkenazi and non-Ashkenazi, with or without colon cancer.
|
11551102 |
2001 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The I1307K variant was analyzed in 242 eligible respondents who were selected because they had a personal or family history of colon cancer.
|
11159880 |
2001 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Studies such as those on APC I1307K and CHEK2 1100delC may suggest the way forward for the identification of 'breast-colon cancer' genes.
|
14574178 |
2001 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The reported association between the APC I1307K mutation and colon cancer risk was supported by a correlation in these data between personal or family history of CRC or polyps and a gene mutation.
|
10756345 |
2000 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
However, a second study indicated that the I1307K mutation did not contribute greatly to the risk of colon cancer in Ashkenazi breast-ovarian cancer families, and a role of mismatch repair deficiency was suggested.
|
9869603 |
1999 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We have shown that the family's phenotype does not result from APC mutations (including the I1307K variant) or from genetic changes in the other known genes that predispose to colon cancer.
|
10092300 |
1999 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The I1307K sequence variant was not found in 67 patients with esophageal cancer, 53 patients with gastric carcinoma (13 MSI-H and 44 MSI-negative), or ten patients with sporadic MSI-H colon cancer.
|
10445854 |
1999 |
rs1463038513
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Significantly, of the 12 individuals who possessed the I1307K mutation, none was diagnosed with colorectal cancer and none had a known first-, second-, or third-degree relative diagnosed with colon cancer.
|
9407954 |
1997 |
rs777980327
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Relationships between adenomatous polyposis coli (APC) mutations, BRAF V600E mutations, and the CpG island methylator phenotype (CIMP) in colon cancer have not been explored.
|
17293392 |
2007 |