rs1042522
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies.
|
18814047 |
2009 |
rs1042522
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Effect of TP53 rs1042522 on the susceptibility of patients to oral squamous cell carcinoma and oral leukoplakia: a meta-analysis.
|
30126398 |
2018 |
rs1042522
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls).
|
16739124 |
2006 |
rs1042522
|
|
|
0.090 |
GeneticVariation |
BEFREE |
P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan.
|
23683469 |
2013 |
rs1042522
|
|
|
0.090 |
GeneticVariation |
BEFREE |
In a large prospective cohort, p53 Arg72Pro Pro/Pro was associated with a 2-fold increased risk of death in all esophageal cancers, whereas MDM2 T309G G/G was associated with a 7-fold increased risk of death in squamous cell carcinoma.
|
19383811 |
2009 |
rs1042522
|
|
|
0.090 |
GeneticVariation |
BEFREE |
In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India.
|
25436609 |
2014 |
rs1042522
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Our data indicate that the TP53 Arg72Pro polymorphism increases the risk for squamous-cell carcinoma mainly in heavy smokers.
|
17059853 |
2007 |
rs1042522
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Polymorphism Arg72Pro of p53 confers susceptibility to squamous cell carcinoma of lungs in a North Indian population.
|
23317414 |
2013 |
rs1042522
|
|
|
0.090 |
GeneticVariation |
BEFREE |
p53 codon 72 ARG/PRO polymorphism is not related to HPV type or lesion grade in low- and high-grade squamous intra-epithelial lesions and invasive squamous carcinoma of the cervix.
|
10449610 |
1999 |
rs1057520001
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results for the p21 Ser31Arg polymorphism suggested that 31Ser is a moderate-risk allele for squamous-cell carcinoma.
|
17059853 |
2007 |
rs1057520004
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The 12th mutation GTG-->GGG (valine-->glycine) at codon 216 was expressed in line SCC-12 clone B along with an apparently normal p53 allele and is to our knowledge a novel mutation.
|
8390283 |
1993 |
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Polymorphism Arg72Pro of p53 confers susceptibility to squamous cell carcinoma of lungs in a North Indian population.
|
23317414 |
2013 |
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Our data indicate that the TP53 Arg72Pro polymorphism increases the risk for squamous-cell carcinoma mainly in heavy smokers.
|
17059853 |
2007 |
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
p53 codon 72 ARG/PRO polymorphism is not related to HPV type or lesion grade in low- and high-grade squamous intra-epithelial lesions and invasive squamous carcinoma of the cervix.
|
10449610 |
1999 |
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In a large prospective cohort, p53 Arg72Pro Pro/Pro was associated with a 2-fold increased risk of death in all esophageal cancers, whereas MDM2 T309G G/G was associated with a 7-fold increased risk of death in squamous cell carcinoma.
|
19383811 |
2009 |
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India.
|
25436609 |
2014 |
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies.
|
18814047 |
2009 |
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan.
|
23683469 |
2013 |
rs1131691014
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls).
|
16739124 |
2006 |
rs587782289
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An SNP, Thr706Ala, in the POLI gene encoding another translesion DNA polymerase was associated with adenocarcinoma and squamous cell carcinoma risk, particularly in individuals of ages < 61 years (OR Ala/Ala + Ala/Thr vs. Thr/Thr = 1.5 and 2.4, respectively).
|
15609317 |
2005 |
rs587783064
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, the FGFR4 Gly388Arg polymorphism and TP53 mutations, as well as their combinations, are excellent predictors of the prognosis for OSCC patients.
|
20127014 |
2010 |
rs754332870
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Analysis of the KRAS gene showed only a G12C variation in one large cell carcinoma (LCC) patient, whereas variants were not found in adenocarcinoma (ADC) and squamous cell carcinoma (SCC) cases.
|
30048458 |
2018 |
rs762846821
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also studied genetically induced SCCs that expressed G12D mutant Kras (Kras G12D) but were deficient for p53.
|
26168291 |
2015 |
rs878854066
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Our data indicate that the TP53 Arg72Pro polymorphism increases the risk for squamous-cell carcinoma mainly in heavy smokers.
|
17059853 |
2007 |
rs878854066
|
|
|
0.080 |
GeneticVariation |
BEFREE |
p53 codon 72 ARG/PRO polymorphism is not related to HPV type or lesion grade in low- and high-grade squamous intra-epithelial lesions and invasive squamous carcinoma of the cervix.
|
10449610 |
1999 |