Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11540654
rs11540654
0.060 GeneticVariation BEFREE Polymorphism Arg72Pro of p53 confers susceptibility to squamous cell carcinoma of lungs in a North Indian population. 23317414

2013

dbSNP: rs11540654
rs11540654
0.060 GeneticVariation BEFREE In a large prospective cohort, p53 Arg72Pro Pro/Pro was associated with a 2-fold increased risk of death in all esophageal cancers, whereas MDM2 T309G G/G was associated with a 7-fold increased risk of death in squamous cell carcinoma. 19383811

2009

dbSNP: rs11540654
rs11540654
0.060 GeneticVariation BEFREE We evaluated the effect of MDM2 SNP309 and its interaction with the p53 Arg72Pro polymorphism on pigmentary phenotypes and skin cancer risk in a nested case-control study within the Nurses' Health Study (NHS) among 219 melanoma cases, 286 squamous cell carcinoma (SCC) cases, 300 basal cell carcinoma (BCC) cases, and 873 controls, and among controls from other studies. 18814047

2009

dbSNP: rs11540654
rs11540654
0.060 GeneticVariation BEFREE Our data indicate that the TP53 Arg72Pro polymorphism increases the risk for squamous-cell carcinoma mainly in heavy smokers. 17059853

2007

dbSNP: rs11540654
rs11540654
0.060 GeneticVariation BEFREE We evaluated the association of the Arg72Pro polymorphism with skin cancer risk among Caucasians in a nested case-control study within the Nurses' Health Study (NHS) (219 melanoma, 286 squamous cell carcinoma (SCC), and 300 basal cell carcinoma (BCC) and 874 controls). 16739124

2006

dbSNP: rs11540654
rs11540654
0.060 GeneticVariation BEFREE p53 codon 72 ARG/PRO polymorphism is not related to HPV type or lesion grade in low- and high-grade squamous intra-epithelial lesions and invasive squamous carcinoma of the cervix. 10449610

1999

dbSNP: rs1042522
rs1042522
0.020 GeneticVariation BEFREE In this study, we analyzed the association of TP53 Pro72Arg polymorphism with squamous cell carcinoma of oral tongue (SCCOT) and esophagus (ESCC) in India. 25436609

2015

dbSNP: rs1042522
rs1042522
0.020 GeneticVariation BEFREE P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan. 23683469

2014

dbSNP: rs759728549
rs759728549
0.010 GeneticVariation BEFREE We also studied genetically induced SCCs that expressed G12D mutant Kras (Kras G12D) but were deficient for p53. 26168291

2015

dbSNP: rs144340710
rs144340710
0.010 GeneticVariation BEFREE We detected four polymorphisms, two of them published for the first time (144+109 C/G and 297+75A/G) and two already published: S62N, in the coding region and related to squamous cell carcinoma (SCC), and 297+17T/C. 18656279

2009

dbSNP: rs28934578
rs28934578
0.010 GeneticVariation BEFREE This was achieved through the retroviral-mediated transduction into normal, primary human esophageal epithelial cells of epidermal growth factor receptor (EGFR), the catalytic subunit of human telomerase (hTERT), and p53(R175H), genes that are frequently altered in human esophageal squamous cell cancer. 17974918

2008

dbSNP: rs573154688
rs573154688
0.010 GeneticVariation BEFREE This was achieved through the retroviral-mediated transduction into normal, primary human esophageal epithelial cells of epidermal growth factor receptor (EGFR), the catalytic subunit of human telomerase (hTERT), and p53(R175H), genes that are frequently altered in human esophageal squamous cell cancer. 17974918

2008