| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
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0.080 | GeneticVariation | BEFREE | In addition to these factors, metabolic syndrome may also be related to genetic factors, the ADIPOQ + 45T> G polymorphism has been associated with serum adiponectin levels, insulin sensitivity, and obesity, which affects adiponectin levels act as protective factor for cardiovascular disease. | 29313754 | 2019 |
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0.080 | GeneticVariation | BEFREE | In conclusion, our meta-analysis found significant increased CVD risk is associated with rs266729 and rs2241766, but not associated with rs1501299. | 29807528 | 2018 |
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0.080 | GeneticVariation | BEFREE | A significant association between rs2241766 in the adiponectin gene and CVD was established by the meta-analysis. | 23972466 | 2014 |
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0.080 | GeneticVariation | BEFREE | To assess whether the prevalence of SNP 45T/G and 276G/T of the adiponectin gene and their haplotypes differ between polycystic ovary syndrome (PCOS) and non-hirsute cycling controls and to investigate the relationship between these haplotypes and risk factors for cardiovascular disease. | 23685884 | 2014 |
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0.080 | GeneticVariation | BEFREE | We examined the impact of rs2241766 and rs1501299 on circulating adiponectin levels, endothelial function and cardiovascular disease risk. | 23041095 | 2013 |
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0.080 | GeneticVariation | BEFREE | The present meta-analysis showed that the associations between rs2241766, rs1501299 and rs266729 in the ADIPOQ and CVD were significant but weak. | 22639977 | 2012 |
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0.080 | GeneticVariation | BEFREE | Two common single nucleotide polymorphisms (SNPs) at the adiponectin locus (45T>G and 276G>T) have been reported to be associated with diabetes and cardiovascular diseases. | 18191060 | 2008 |
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0.080 | GeneticVariation | BEFREE | We sought to examine the associations of five variants of APM1 gene (C-11365G, A-4034C, A-3964G, T45G, and G276T) with the risk of cardiovascular diseases (CVDs) in a larger cohort of diabetic patients. | 15855354 | 2005 |