|
rs25487
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Significantly higher total chromosomal aberrations were detected in individuals with homozygous variant polymorphism in XRCC1 Arg399Gln gene as compared to those with heterozygous and homozygous wild-type genotypes (2.20, 1.89 and 1.48%, respectively; P = 0.01).
|
21858514 |
2012 |
|
rs25487
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We investigated the influence of tobacco smoke on cytogenetic parameters (chromosomal aberrations and micronuclei) and the influence of XRCC1 arg399gln polymorphism on the cytogenetic parameters of the exposed subjects.
|
21843798 |
2011 |
|
rs25487
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The focal aim of this study was to assess the frequency of chromosomal aberrations (CA) including chromatid type aberrations (CTA) and chromosomal type aberrations (CSA), micronucleus (MN) and XRCC1 399 Arg/Gln polymorphism in the peripheral blood lymphocytes of 27 petrol pump workers and same number of controls to explore the possible cytogenetic risk on occupational exposure to petrol vapors.
|
20652227 |
2010 |
|
rs25487
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Moreover, the clearest differences were found for rs13181 in ERCC2 and rs25487 in XRCC1 between CLL patients with unfavorable cytogenetic aberrations and controls.
|
19484764 |
2009 |
|
rs25487
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The effects of genetic polymorphisms in the NQO1 (rs1800566), MPO (rs2333227), and XRCC1 (rs25487) genes on benzene-induced chromosome abnormalities were assessed in 108 benzene-exposed workers and 33 office workers.
|
18214807 |
2008 |
|
rs25487
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We analysed the associations between genetic polymorphisms in genes coding for DNA repair enzymes XPD (exon 23 A --> C, K751Q), XPG (exon 15 G --> C, D1104H), XPC (exon 15 A --> C, K939Q), XRCC1 (exon 10 G --> A, R399Q) and XRCC3 (exon 7 C --> T, T241 M) and the levels of chromosomal aberrations (CAs) and single-strand breaks (SSBs) in peripheral lymphocytes in a central European population.
|
14729591 |
2004 |
|
rs77375493
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Among 50 PMF patients, CALR mutations were detected in 11 (22.0%) and were also associated with higher platelet counts (P=0.035) and trended to a lower rate of cytogenetic abnormalities (P=0.059) than the JAK2 V617F mutation.
|
26130950 |
2015 |
|
rs77375493
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Cytogenetic abnormalities and molecular markers such as JAK2 V617F, ASXL1, and CALR mutations have also been identified as prognostic variables.
|
25189726 |
2014 |
|
rs77375493
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We studied 176 patients, all enrolled on prospective treatment trials, for secondary chromosomal aberrations and mutations in N-/KRAS, KIT, FLT3, and JAK2 (V617F) genes.
|
23115274 |
2013 |
|
rs77375493
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Translocation t(1;9) is a recurrent cytogenetic abnormality associated with progression of essential thrombocythemia patients displaying the JAK2 V617F mutation.
|
21376394 |
2011 |
|
rs13181
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our study is focused on the extent of any such chromosomal aberrations with respect to chromium levels in the blood of welders as well as on the tentative modulating role of polymorphisms in DNA repair genes XPD Lys751Gln, XPG Asn114His, XPC Lys939Gln, hOGG1 Ser326Cys and XRCC1 Arg399Gln on chromosomal damage.
|
21858514 |
2012 |
|
rs13181
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Moreover, the clearest differences were found for rs13181 in ERCC2 and rs25487 in XRCC1 between CLL patients with unfavorable cytogenetic aberrations and controls.
|
19484764 |
2009 |
|
rs13181
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We analysed the associations between genetic polymorphisms in genes coding for DNA repair enzymes XPD (exon 23 A --> C, K751Q), XPG (exon 15 G --> C, D1104H), XPC (exon 15 A --> C, K939Q), XRCC1 (exon 10 G --> A, R399Q) and XRCC3 (exon 7 C --> T, T241 M) and the levels of chromosomal aberrations (CAs) and single-strand breaks (SSBs) in peripheral lymphocytes in a central European population.
|
14729591 |
2004 |
|
rs1042522
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study aimed to examine the frequency of chromosomal aberrations and the mitotic index in patients with chronic hepatitis B and their possible association with p53 gene exon 4 codon 72 Arg72Pro (Ex4+119 G>C; rs1042522) polymorphism.
|
22892830 |
2012 |
|
rs1131691014
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study aimed to examine the frequency of chromosomal aberrations and the mitotic index in patients with chronic hepatitis B and their possible association with p53 gene exon 4 codon 72 Arg72Pro (Ex4+119 G>C; rs1042522) polymorphism.
|
22892830 |
2012 |
|
rs2228001
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our study is focused on the extent of any such chromosomal aberrations with respect to chromium levels in the blood of welders as well as on the tentative modulating role of polymorphisms in DNA repair genes XPD Lys751Gln, XPG Asn114His, XPC Lys939Gln, hOGG1 Ser326Cys and XRCC1 Arg399Gln on chromosomal damage.
|
21858514 |
2012 |
|
rs759412116
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Significantly higher total chromosomal aberrations were detected in individuals with homozygous variant polymorphism in XRCC1 Arg399Gln gene as compared to those with heterozygous and homozygous wild-type genotypes (2.20, 1.89 and 1.48%, respectively; P = 0.01).
|
21858514 |
2012 |
|
rs878854066
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study aimed to examine the frequency of chromosomal aberrations and the mitotic index in patients with chronic hepatitis B and their possible association with p53 gene exon 4 codon 72 Arg72Pro (Ex4+119 G>C; rs1042522) polymorphism.
|
22892830 |
2012 |
|
rs1042522
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the TP53 gene Arg72Pro polymorphism appreciably influence on occurrence of chromosome aberrations</span> in cancer.
|
20512840 |
2010 |
|
rs1131691014
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the TP53 gene Arg72Pro polymorphism appreciably influence on occurrence of chromosome aberrations</span> in cancer.
|
20512840 |
2010 |
|
rs878854066
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the TP53 gene Arg72Pro polymorphism appreciably influence on occurrence of chromosome aberrations</span> in cancer.
|
20512840 |
2010 |
|
rs2228001
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We analysed the associations between genetic polymorphisms in genes coding for DNA repair enzymes XPD (exon 23 A --> C, K751Q), XPG (exon 15 G --> C, D1104H), XPC (exon 15 A --> C, K939Q), XRCC1 (exon 10 G --> A, R399Q) and XRCC3 (exon 7 C --> T, T241 M) and the levels of chromosomal aberrations (CAs) and single-strand breaks (SSBs) in peripheral lymphocytes in a central European population.
|
14729591 |
2004 |
|
rs759412116
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We analysed the associations between genetic polymorphisms in genes coding for DNA repair enzymes XPD (exon 23 A --> C, K751Q), XPG (exon 15 G --> C, D1104H), XPC (exon 15 A --> C, K939Q), XRCC1 (exon 10 G --> A, R399Q) and XRCC3 (exon 7 C --> T, T241 M) and the levels of chromosomal aberrations (CAs) and single-strand breaks (SSBs) in peripheral lymphocytes in a central European population.
|
14729591 |
2004 |
|
rs1383997
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Replication 1 supported the association of rs1383997 (8q13.3) and rs2824215 (21q21.1) in CAtot and rs983889 (5p15.1) in CTA analysis.
|
30368896 |
2019 |
|
rs2824215
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Replication 1 supported the association of rs1383997 (8q13.3) and rs2824215 (21q21.1) in CAtot and rs983889 (5p15.1) in CTA analysis.
|
30368896 |
2019 |