Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3025053
rs3025053
0.020 GeneticVariation BEFREE In this case-control study of 371 CRC cases and 246 healthy controls, we analyzed the association between one SNP (rs1137188G > A) in the KRAS gene and four SNPs (rs3025039C > T, rs3025040C > T, rs3025053G > A and rs10434A > G) in the VEGF gene and CRC susceptibility by the improved multiplex ligase detection reaction (iMLDR) method. 28328959

2017

dbSNP: rs833061
rs833061
0.020 GeneticVariation BEFREE <i>VEGFA</i> rs833061 polymorphism is significantly associated with the therapeutic efficiency of bevacizumab in CRC patients. 29285265

2017

dbSNP: rs3025053
rs3025053
0.020 GeneticVariation BEFREE The aim of this study was to investigate the associations of three VEGF 3'-UTR polymorphisms (1451C > T [rs3025040], 1612G > A [rs10434], and 1725G > A [rs3025053]) and MetS with colorectal cancer (CRC) susceptibility in Koreans. 25423914

2014

dbSNP: rs833061
rs833061
0.020 GeneticVariation BEFREE The VEGFA rs833061 SNP is associated with the ORR, and the FLT1 rs9513070 SNP and FLT1 GCA haplotypes are associated with PFS and OS in advanced CRC patients treated with cytotoxic chemotherapy plus bevacizumab. 25139485

2014

dbSNP: rs3025039
rs3025039
0.010 GeneticVariation BEFREE The minor allele of rs3025039 was related to increased risk of CRC in East Asian population (allelic model: 1.25 [1.01-1.54]). 31637880

2019

dbSNP: rs10434
rs10434
0.010 GeneticVariation BEFREE In this case-control study of 371 CRC cases and 246 healthy controls, we analyzed the association between one SNP (rs1137188G > A) in the KRAS gene and four SNPs (rs3025039C > T, rs3025040C > T, rs3025053G > A and rs10434A > G) in the VEGF gene and CRC susceptibility by the improved multiplex ligase detection reaction (iMLDR) method. 28328959

2017

dbSNP: rs3025040
rs3025040
0.010 GeneticVariation BEFREE In this case-control study of 371 CRC cases and 246 healthy controls, we analyzed the association between one SNP (rs1137188G > A) in the KRAS gene and four SNPs (rs3025039C > T, rs3025040C > T, rs3025053G > A and rs10434A > G) in the VEGF gene and CRC susceptibility by the improved multiplex ligase detection reaction (iMLDR) method. 28328959

2017

dbSNP: rs699947
rs699947
0.010 GeneticVariation BEFREE This study aimed to explore the effects of vascular endothelial growth factor A (<i>VEGFA</i>) gene polymorphisms (rs699947 and rs833061) on Bevacizumab (BEV) treatment in colorectal cancer (CRC) patients. 29285265

2017

dbSNP: rs914956206
rs914956206
0.010 GeneticVariation BEFREE Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model. 25359494

2015

dbSNP: rs1222213359
rs1222213359
0.010 GeneticVariation BEFREE In the present study we evaluated single nucleotide polymorphisms (SNPs) -2578C > A, -1154G > A, and +936C > T in the VEGF gene, and their prognostic value for patients operated on for colorectal cancer (CRC). 20187681

2010