Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913530
rs121913530
G 0.700 CausalMutation CLINVAR Mutant KRAS codon 12 and 13 alleles in patients with metastatic colorectal cancer: assessment as prognostic and predictive biomarkers of response to panitumumab. 23182985

2013

dbSNP: rs17851045
rs17851045
G 0.700 CausalMutation CLINVAR Massively parallel tumor multigene sequencing to evaluate response to panitumumab in a randomized phase III study of metastatic colorectal cancer. 23325582

2013

dbSNP: rs17851045
rs17851045
A 0.700 CausalMutation CLINVAR Massively parallel tumor multigene sequencing to evaluate response to panitumumab in a randomized phase III study of metastatic colorectal cancer. 23325582

2013

dbSNP: rs112445441
rs112445441
T 0.700 CausalMutation CLINVAR Association of KRAS G13D tumor mutations with outcome in patients with metastatic colorectal cancer treated with first-line chemotherapy with or without cetuximab. 22734028

2012

dbSNP: rs112445441
rs112445441
T 0.700 CausalMutation CLINVAR Inhibition of MEK and PI3K/mTOR suppresses tumor growth but does not cause tumor regression in patient-derived xenografts of RAS-mutant colorectal carcinomas. 22392911

2012

dbSNP: rs121913530
rs121913530
G 0.700 CausalMutation CLINVAR Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. 22722830

2012

dbSNP: rs17851045
rs17851045
G 0.700 CausalMutation CLINVAR Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. 22722830

2012

dbSNP: rs17851045
rs17851045
A 0.700 CausalMutation CLINVAR Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. 22722830

2012

dbSNP: rs1057519725
rs1057519725
A 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs112445441
rs112445441
T 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs112445441
rs112445441
G 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs112445441
rs112445441
T 0.700 CausalMutation CLINVAR Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations. 21398618

2011

dbSNP: rs121913238
rs121913238
T 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913240
rs121913240
C 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913240
rs121913240
A 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913527
rs121913527
G 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913528
rs121913528
T 0.700 GeneticVariation CLINVAR Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations. 21398618

2011

dbSNP: rs121913529
rs121913529
G 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913529
rs121913529
A 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913529
rs121913529
A 0.700 CausalMutation CLINVAR Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations. 21398618

2011

dbSNP: rs121913529
rs121913529
T 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913530
rs121913530
G 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913530
rs121913530
T 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913530
rs121913530
A 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011

dbSNP: rs121913535
rs121913535
T 0.700 CausalMutation CLINVAR Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. 21228335

2011