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rs10159239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Single Nucleotide Polymorphism rs10159239 was examined by logistic regression with known risk factors for Coronary artery disease and remained significant (0.035).
|
31639433 |
2020 |
|
rs133049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The primary aim of this study was to investigate whether two leading ANRIL SNPs, namely, rs133049 and rs3217992, were associated with plasma levels of C-reactive protein among a large cohort of in-patients with CHD (n = 933).
|
31770616 |
2020 |
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rs3217992
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ANRIL polymorphisms (rs1333049 and rs3217992) in relation to plasma CRP levels among in-patients with CHD.
|
31770616 |
2020 |
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rs72658855
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A non-significant association was reported in recessive inheritance model for variant (CC+CT) vs. TT OR 0.56(0.16-1.95), P<0.36. and in dominant inheritance model for variant CC vs. (CT+TT) OR 2.8(1.07-7.34),P<0.032 .In case of allelic comparison, it was indicated that the LDLR rs2228671-T allele was associated with an increased risk of developing risk of CAD compared to C allele OR=2.4, 95% CI (1.05-5.64) P< 0.036 .Our findings showed that LDLR rs72658855 C>T gene variability is associated with an increased susceptibility to coronary artery disease in codominant inheritance model for variant CC vs. CT OR 1.7(1.1-2.6), P<0.015 and in dominant inheritance model for variant CC vs. (CT+TT) OR 1.66(1.07-2.58),P<0.0.02.
|
31613733 |
2020 |
|
rs756601757
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We speculate that this mutation [Arg196Trp] in the USF1 gene might be associated with FCHL and early-onset coronary heart disease in this family.
|
31725952 |
2020 |
|
rs891512
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1799983-T and rs891512-A alleles and interaction between rs1799983 and smoking were all risk factors of CHD.
|
31567371 |
2020 |
|
rs972655070
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We speculate that this mutation [Arg196Trp] in the USF1 gene might be associated with FCHL and early-onset coronary heart disease in this family.
|
31725952 |
2020 |
|
rs1050993
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study suggests that MTR polymorphisms (rs1770449 and rs1050993) may be associated with the risk of CHDs and modify the relation between maternal folate intake and CHDs.
|
30911047 |
2019 |
|
rs1051339
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Further, we characterized a second common exonic coding variant (rs1051339), which is predicted to alter LIPA signal peptide cleavage similarly to rs1051338, yet is not linked to intronic variants. rs1051339 also does not impact LIPA function in vitro and confers no coronary artery disease risk.
|
31645127 |
2019 |
|
rs10738606
|
|
|
0.010 |
GeneticVariation |
BEFREE |
And age-based subgroup tests indicated that rs2383205 and r</span>s10738606 were associated with CHD</span> among individuals, respectively (p < .05).
|
31496134 |
2019 |
|
rs12165908
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype analyses revealed that minor alleles in <i>TBX1</i>: rs12165908 C > G [odds ratio (OR) = 2.64; 95% confidence interval (CI) = 1.87-3.73, <i>p</i> = 3.03 × 10<sup>-8</sup>] and <i>GATA6</i>: rs143085291 C > T (OR = 2.49; 95% CI = 1.18-5.29, <i>p</i> = 0.01) increased CHD risk significantly.
|
31013439 |
2019 |
|
rs1266235110
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It was observed that Haplotype-1(rs1799941 G allele-P156L P allele-D356 N D allele) was associated with increased CHD risk, while Haplotype-2 (rs1799941 rare A allele-P156L C allele- D356 N G allele) was correlated with the decreased CHD risk (p = 0.0167).
|
31111369 |
2019 |
|
rs12704673
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two novel loci were associated with birthweight and adult coronary artery disease (rs2870463 in CTRB1) and with birthweight and adult waist circumference (rs12704673 in CALCR).
|
30858448 |
2019 |
|
rs12921862
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two variants were found to confer a risk of CHDs: variant rs4720169 of <i>TBX20</i> in which the OR for the heterozygous state was 1.88 (95% confidence interval [CI]: 1.12-3.14, <i>p</i> = 0.010), whereas the OR for the homozygous state was 3.82 (95% CI: 1.18-12.3, <i>p</i> = 0.010); and variant rs12921862 of <i>AXIN1</i> in which the OR for the heterozygous state was 4.15 (95% CI: 2.42-7.10; <i>p</i> ≤ 0.001), whereas the OR for the homozygous state was 9.2 (95% CI: 1.31-64.7, <i>p</i> = 0.008) for allele A.
|
31524541 |
2019 |
|
rs139401390
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genome-wide association study suggests impact of chromosome 10 rs139401390 on kidney function in patients with coronary artery disease.
|
30809046 |
2019 |
|
rs143085291
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotype analyses revealed that minor alleles in <i>TBX1</i>: rs12165908 C > G [odds ratio (OR) = 2.64; 95% confidence interval (CI) = 1.87-3.73, <i>p</i> = 3.03 × 10<sup>-8</sup>] and <i>GATA6</i>: rs143085291 C > T (OR = 2.49; 95% CI = 1.18-5.29, <i>p</i> = 0.01) increased CHD risk significantly.
|
31013439 |
2019 |
|
rs146292819
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of rs146292819 Polymorphism in ABCA1 Gene with the Risk of Coronary Artery Disease in Pakistani Population.
|
30945099 |
2019 |
|
rs1743963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, both the GG genotype of <i>SGK1</i> rs1743963 and AA genotype of <i>SGK1</i> rs1763509 were associated with a higher risk of depression in CHD patients; for rs1763509, the Patient Health Questionnaire-9 (PHQ-9) scores in the carriers of the risk genotype for comorbid depression, AA, were significantly higher than in GG and AG carriers (<i>P</i> = 0.008).
|
31632443 |
2019 |
|
rs1761667
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CD36 gene polymorphism rs1761667 (G > A) is associated with hypertension and coronary artery disease in an Iranian population.
|
31185924 |
2019 |
|
rs1763509
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, both the GG genotype of <i>SGK1</i> rs1743963 and AA genotype of <i>SGK1</i> rs1763509 were associated with a higher risk of depression in CHD patients; for rs1763509, the Patient Health Questionnaire-9 (PHQ-9) scores in the carriers of the risk genotype for comorbid depression, AA, were significantly higher than in GG and AG carriers (<i>P</i> = 0.008).
|
31632443 |
2019 |
|
rs1770449
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Without maternal periconceptional folate intake, the risk of CHDs among women carrying the rs1770449 "CT or CC" genotype or the rs1050993 "AG or AA" genotype in MTR was 3.262(95%CI: 1.656-6.429) or 3.263(95%CI: 1.656-6.429) times greater than the aOR in women carrying wild genotype, respectively.
|
30911047 |
2019 |
|
rs1799930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a hospital-based case-control study to investigate the association of NAT2 gene polymorphisms (rs1799930 G/A, rs1208 A/G, and rs1799931 G/A) and the combinations of PAHs exposure and genetic variants with the risk of CHDs.
|
31254350 |
2019 |
|
rs1799931
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a hospital-based case-control study to investigate the association of NAT2 gene polymorphisms (rs1799930 G/A, rs1208 A/G, and rs1799931 G/A) and the combinations of PAHs exposure and genetic variants with the risk of CHDs.
|
31254350 |
2019 |
|
rs1799941
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It was observed that Haplotype-1(rs1799941 G allele-P156L P allele-D356 N D allele) was associated with increased CHD risk, while Haplotype-2 (rs1799941 rare A allele-P156L C allele- D356 N G allele) was correlated with the decreased CHD risk (p = 0.0167).
|
31111369 |
2019 |
|
rs1800872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of IL-8-251 A/T rs4073 and IL-10 rs1800872 -592C/A Polymorphisms and Coronary Artery Disease in North Indian Population.
|
30073578 |
2019 |