Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs429358
rs429358
0.020 GeneticVariation BEFREE <b>Aim:</b> To explore the association of APOE polymorphism (rs7412:526C>T and rs429358:388T>C) with glucose, lipid and serum uric acid (UA) metabolism in patients with hypertension or coronary heart disease (CHD). 31559922

2019

dbSNP: rs6882076
rs6882076
0.010 GeneticVariation BEFREE <b>Conclusions</b>: The results of the present study suggest that the <i>TIMD4</i> rs6882076 SNP is associated with decreased risk of CHD and IS in our study population. 31337960

2019

dbSNP: rs7041
rs7041
GC
0.030 GeneticVariation BEFREE <b>Objectives</b>: The vitamin D binding protein encoded by the <i>GC</i> gene contains two single nucleotide polymorphisms (rs4588 and rs7041) that have been associated with disease outcome, these include periodontitis coronary heart disease and hypertension. 31559882

2019

dbSNP: rs9982601
rs9982601
0.810 GeneticVariation BEFREE <i>Background</i>.The coronary heart disease (CHD) risk locus on 21q22 (lead SNP rs9982601) lies within a "gene desert." 28458444

2017

dbSNP: rs8259
rs8259
BSG
0.010 GeneticVariation BEFREE <i>BSG</i> rs8259 TT genotype was associated with a decreased risk of CHF (OR = 0.83, 95% CI = 0.72-0.96, <i>p</i> = 0.010), especially in patients with hypertension (OR = 0.80, 95% CI = 0.68-0.95, <i>p</i> = 0.011) and coronary heart disease (OR = 0.81, 95% CI = 0.69-0.96, <i>p</i> = 0.013) after adjustment for multiple cardiovascular risk factors. 28230811

2017

dbSNP: rs4646903
rs4646903
0.010 GeneticVariation BEFREE 1.The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of coronary heart disease and cigarette smoking-related lung cancer. 19650794

2010

dbSNP: rs1805017
rs1805017
0.040 GeneticVariation BEFREE 14 association studies focusing on three polymorphisms (A379V, V279F and R92H) in PLA2G7 gene and risk of CHD were included in meta-analysis, covering a total of 8,280 cases and 5,656 controls. 20926117

2010

dbSNP: rs1800588
rs1800588
0.720 GeneticVariation BEFREE 557 men aged 45-74 with stable coronary artery disease and 560 paired controls were genotyped for rs1800588. 23874450

2013

dbSNP: rs662
rs662
0.100 GeneticVariation BEFREE Coronary artery disease risk in Chinese type 2 diabetics: is there a role for paraxonase 1 gene (Q192R) polymorphism? 11375798

2001

dbSNP: rs1541861
rs1541861
0.010 GeneticVariation BEFREE CHD risk was significantly higher among men with the variant allele at the rs1541861 locus (intron 8 A/C) than men without it (adjusted odds ratio 1.5 [95% confidence interval 1.1-2.1]). 16804086

2006

dbSNP: rs5443
rs5443
0.020 GeneticVariation BEFREE C825T polymorphism in the G protein beta3 subunit gene (GNB3) has been associated with arterial hypertension, coronary artery disease and myocardial infarction. 10704626

2000

dbSNP: rs6020
rs6020
F5
0.020 GeneticVariation BEFREE Arg485Lys polymorphism of factor V increases the risk of coronary artery disease in a Chinese population. 11776127

2000

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Glu298-->Asp polymorphism of the eNOS gene appears to be associated with the presence, extent, and severity of angiographically assessed coronary artery disease. 12010932

2002

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE M235T and T174M variants do not contribute to the increased risk of CHD or hypertension in the Indian population. 12938141

2003

dbSNP: rs1267969615
rs1267969615
ACE
0.080 GeneticVariation BEFREE M235T and T174M variants do not contribute to the increased risk of CHD or hypertension in the Indian population. 12938141

2003

dbSNP: rs1217691063
rs1217691063
0.100 GeneticVariation BEFREE C677T mutation of methylenetetrahydrofolate reductase gene and serum homocysteine levels in Turkish patients with coronary artery disease. 15648053

2006

dbSNP: rs1199475313
rs1199475313
0.010 GeneticVariation BEFREE T64A polymorphism in beta3-adrenergic receptor gene (ADRB3) and coronary heart disease: a case-cohort study and meta-analysis. 18088254

2008

dbSNP: rs7903146
rs7903146
0.720 GeneticVariation BEFREE rs7903146 T allele is associated with diabetes and, in non-diabetic individuals, with a higher prevalence and severity of coronary artery disease and cardiovascular events. name of registry site (see list below), registration number, trial registration URL in brackets. 19924244

2009

dbSNP: rs7025486
rs7025486
0.020 GeneticVariation BEFREE rs7025486 was genotyped in 1386 CHD cases and 3532 controls and was associated with CHD [odds ratio (OR) of 1.16, 95% confidence interval (CI) 1.05-1.29, P= 0.003]. 21444365

2012

dbSNP: rs1799983
rs1799983
0.100 GeneticVariation BEFREE Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characterized as a risk factor of hypertension and coronary artery disease. 21816783

2011

dbSNP: rs1049353
rs1049353
0.010 GeneticVariation BEFREE G1359A polymorphism in the cannabinoid receptor-1 gene is associated with the presence of coronary artery disease in patients with type 2 diabetes. 22138970

2012

dbSNP: rs2943634
rs2943634
0.830 GeneticVariation BEFREE rs2943634 C/A single nucleotide polymorphism (SNP), located in a non coding region of chromosome 2q36.3, has been associated with coronary artery disease in two genome wide association studies. 22207032

2012

dbSNP: rs174547
rs174547
0.830 GeneticVariation BEFREE rs174547 in FADS1 may contribute to the susceptibility of CHD by altering HDL-C and TG levels in Chinese individuals. 22490578

2012

dbSNP: rs1181860747
rs1181860747
0.010 GeneticVariation BEFREE Gly1057Asp polymorphism of insulin receptor substrate-2 is associated with coronary artery disease in the Taiwanese population. 23216712

2012

dbSNP: rs1805097
rs1805097
0.010 GeneticVariation BEFREE Gly1057Asp polymorphism of insulin receptor substrate-2 is associated with coronary artery disease in the Taiwanese population. 23216712

2012