rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
ANRIL polymorphisms (rs1333049 and rs3217992) in relation to plasma CRP levels among in-patients with CHD.
|
31770616 |
2020 |
rs671
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism is an established genetic risk of hypertension, diabetes, and coronary heart diseases in Asian population.
|
30846829 |
2020 |
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Gender-based subgroup tests showed that four polymorphisms (rs75227345, rs2383205, rs10738606 and rs1333049) were associated with CHD in males (p < .05).
|
31496134 |
2019 |
rs671
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Six common variants at ALDH2 gene, including rs2339840, rs4648328, rs4767939, rs11066028, rs16941669, and rs671, were selected to test the associations of those polymorphisms with the cardiovascular outcome in patients with CHD after PCI.
|
29742731 |
2018 |
rs671
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management.
|
29960587 |
2018 |
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Association Study Between Coronary Artery Disease and rs1333049 Polymorphism at 9p21.3 Locus in Italian Population.
|
28639227 |
2017 |
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our study aims to explore the association of rs7025486 single-nucleotide polymorphisms (SNP) in DAB2IP and rs1333049 on chromosome 9p21.3 with the coronary artery disease in Chinese population.
|
28962556 |
2017 |
rs10757274
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Interestingly, the haplotype AA (rs10757274 and rs1333042) of CDKN2BAS was associated with decreased the risk of CHD in men (OR = 0.72, 95% CI: 0.55 - 0.95, P = 0.022).
|
27741513 |
2016 |
rs1333049
|
|
|
0.900 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Despite excellent power, the 9p21 locus SNP (rs1333049) was only modestly associated with MI (HR = 1.09, p-value = 0.02) and marginally with CHD (HR = 1.06, p-value = 0.08).
|
26950853 |
2016 |
rs671
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Previous studies demonstrated that aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism, which eliminates ALDH2 activity down to 1%-6%, is a susceptibility gene for coronary disease.
|
27191745 |
2016 |
rs10757274
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Association of the rs10757274 SNP with coronary artery disease in a small group of a Pakistani population.
|
25592106 |
2015 |
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The leading coronary artery disease-associated SNP rs1333049 was associated with coronary artery disease; however, none of the 9p21 SNP evaluated in the present study were associated with extreme longevity.
|
25257646 |
2015 |
rs671
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We genotyped rs671 of ALDH2 in 96 coronary heart disease (CHD) patients with four methods including high resolution melting analysis (HRM), TaqMan allelic discrimination assay (TaqMan), allele-specific PCR (AS-PCR) and pyrosequencing.
|
25803854 |
2015 |
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
This study confirms the association between 9p21 (rs1333049) and fatal CHD in a Norwegian population-based cohort.
|
24728607 |
2014 |
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our case-control study and meta-analysis suggest that rs1333049 is a useful risk marker of CHD.
|
24930384 |
2014 |
rs1333049
|
|
C |
0.900 |
GeneticVariation |
GWASCAT |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |
rs671
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The association between the aldehyde dehydrogenase 2 (ALDH2, rs671) genotypes and the estimated glomerular filtration rate (eGFR) was investigated in Japanese hypertensive patients with/without coronary artery disease or with ischemic heart failure (HF), and age/sex-matched normotensive healthy controls.
|
24067347 |
2014 |
rs671
|
|
|
0.900 |
GeneticVariation |
BEFREE |
ALDH2 Glu504Lys polymorphism and susceptibility to coronary artery disease and myocardial infarction in East Asians: a meta-analysis.
|
24333098 |
2014 |
rs671
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The Glu504Lys polymorphism of aldehyde dehydrogenase 2 contributes to development of coronary artery disease.
|
25263942 |
2014 |
rs10757274
|
|
|
0.900 |
GeneticVariation |
BEFREE |
A case-control study to investigate the association of the 9p21 single nucleotide polymorphisms (SNPs) rs10757274 and rs10757278 (known to be associated with coronary artery disease [CAD] risk) with peripheral arterial disease (PAD), in a Han Chinese population.
|
23569135 |
2013 |
rs1333049
|
|
|
0.900 |
GeneticVariation |
GWASDB |
A genome-wide association study of a coronary artery disease risk variant.
|
23364394 |
2013 |
rs671
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Our meta-analysis results showed that the A variant of the ALDH2 rs671 polymorphism may be associated with increase risks of CHD (odds ratios [OR]=1.36, 95% confidence interval [CI]=1.06-1.75, p=0.017) and MI (OR=1.64, 95% CI=1.22-2.20, p=0.001).
|
23697560 |
2013 |
rs10757274
|
|
|
0.900 |
GeneticVariation |
BEFREE |
The Ch9p21 SNPs rs1333049 (OR 1.17; 95% confidence limits 1.11-1.24) and rs10757274 (OR 1.17; 1.09-1.26), MIA3 rs17465637 (OR 1.10; 1.04-1.15), Ch2q36 rs2943634 (OR 1.08; 1.03-1.14), APC rs383830 (OR 1.10; 1.02, 1.18), MTHFD1L rs6922269 (OR 1.10; 1.03, 1.16), CXCL12 rs501120 (OR 1.12; 1.04, 1.20), and SMAD3 rs17228212 (OR 1.11; 1.05, 1.17) were all associated with CHD risk, but not with the CHD biomarkers and risk factors measured.
|
21804106 |
2012 |
rs10757274
|
|
G |
0.900 |
GeneticVariation |
GWASDB |
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.
|
22751097 |
2012 |