DisGeNET - a database of gene-disease associations

Mental Depression, C0011570

Variant: rs9939609 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs9939609

FTO

0.030

GeneticVariation

BEFREE

Linear regression models were performed to test for association between rs9939609 and body mass index (BMI), and for the interaction between rs9939609 and depression status for an effect on BMI.

28642257

2017

dbSNP:

rs9939609

FTO

0.030

GeneticVariation

BEFREE

The genotype score, calculated with or without FTO rs9939609, and adjusted for the same covariates, was not associated with depression status.

26717541

2015

dbSNP:

rs9939609

FTO

0.030

GeneticVariation

BEFREE

In conclusion, we provide the first evidence that the FTO rs9939609 A variant may be associated with a lower risk of depression independently of its effect on BMI.

23164817

2013