| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | BEFREE | The TT genotype of rs3856806 in PPAR<i>γ</i> had an increased risk for diabetes. | 29849618 | 2018 |
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|
0.080 | GeneticVariation | BEFREE | The C1431T polymorphism of peroxisome proliferator activated receptor-γ (PPAR-γ) gene is related to diabetes and metabolic-syndrome. | 25896411 | 2015 |
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|
0.080 | GeneticVariation | BEFREE | The C1431T polymorphism in peroxisome proliferator-activated receptor-γ (PPARγ) has been shown to be associated with diabetes, obesity, and metabolic syndrome. | 21643757 | 2012 |
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|
0.080 | GeneticVariation | BEFREE | Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has been shown to be associated with body weight, but its association with diabetes is controversial. | 21795447 | 2011 |
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|
0.080 | GeneticVariation | BEFREE | Studies on the association of the Pro12Ala and C1431T polymorphisms of PPAR? with diabetes and obesity have revealed extensive population-dependent variations. | 19805902 | 2009 |
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|
0.080 | GeneticVariation | BEFREE | Based on published data from four populations, the date of origin of the diabetes protective PPARG Ala12 variant was estimated using both allele frequency and linkage disequilibrium (LD) with the C1431T single nucleotide polymorphism in exon 6 of the PPARG gene. | 15994875 | 2005 |
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|
0.080 | GeneticVariation | BEFREE | We have shown previously that the linked T allele of the C1431T polymorphism influences Ala12-associated diabetes risk and that the 2 polymorphisms have opposing associations with body weight. | 15486307 | 2004 |
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|
0.080 | GeneticVariation | BEFREE | The Pro12Ala polymorphism was more associated with plasma lipids and fasting glucose concentrations, whereas the C1431T polymorphism was related to the risk of diabetes. | 14729856 | 2004 |