rs10010131
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We genotyped the WFS1 SNPs rs10010131, rs752854 and rs734312 (H611R) in 3,548 DPP participants and performed Cox regression analysis using genotype, intervention and their interactions as predictors of diabetes incidence.
|
18060660 |
2008 |
rs1004446
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three single nucleotide polymorphisms were associated with increased diabetes risk (rs10517086_A [<i>P</i> = 0.03], rs1534422_G [<i>P</i> = 0.006], and rs2327832_G [<i>P</i> = 0.03] in <i>TNFAIP3</i>) and one with decreased risk (rs1004446_A in <i>INS</i> [<i>P</i> = 0.006]).
|
28903990 |
2017 |
rs10069690
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Chinese polymyositis (PM) patients (n =291), dermatomyositis (DM) patients (n=526) and ethnically-matched healthy controls (n =968) were genotyped for the CCL21 region SNPs (rs951005 and rs2492358), ERBB3 (rs2292239 and rs11171739), and TERT (rs2853676 and rs10069690), by using the Sequenom MassArray system.
|
26320593 |
2015 |
rs10084572
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.
|
31451708 |
2019 |
rs10116772
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variants in strong correlation with rs10116772 have been associated with elevated plasma glucose levels and diabetes.
|
29436472 |
2018 |
rs1013773109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.
|
23747250 |
2013 |
rs1020608562
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We aimed to investigate the associations of fractalkine receptor (CX3CR1) V249I, T280M and CCR5-59029 A/G gene polymorphisms in chronic renal failure (CRF) subjects undergoing hemodialysis and to evaluate possible associations of these polymorphisms with hypertension (HT), diabetes mellitus (DM) and atherosclerosis (AS).
|
27118566 |
2016 |
rs1022113606
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We used the prospective Copenhagen General Population Study and Copenhagen City Heart Study and genotyped 95,871 individuals for the rs1799895 R213G variation in the SOD3 gene, of which 4498 had diabetes.
|
26844281 |
2015 |
rs10224002
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
|
29703844 |
2018 |
rs10224210
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.
|
31451708 |
2019 |
rs1024611
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Multivariate Cox regression analysis, taking into the account the recipient's sex, age and BMI, as well as the number of G alleles of the CCL2 rs1024611 polymorphism, revealed that this polymorphism is an independent risk factor for post-transplant diabetes.
|
26802601 |
2016 |
rs1024611
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Besides, rs1024611 SNP was slightly correlated with increased DFUs susceptibility in patients with DM.
|
29995756 |
2018 |
rs1033656351
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the Prevalence, Prediction, and Prevention of Diabetes in Botnia study, the minor allele in the missense functional variant rs1718119 (A348T) in P2RX7 was associated with increased insulin sensitivity and secretion, consistent with its known effect on increased pore function.
|
25719930 |
2015 |
rs1036483919
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The heterozygous T130I mutation was the unique functional gene variation that could explain diabetes phenotype.
|
25361053 |
2014 |
rs1036483919
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Mutation p.T130I was associated with both early-onset and late-onset diabetes and caused downregulated HNF4A expression, whereas HNF1A polymorphisms p.I27L and p.S487N were associated with the age of diagnosis of diabetes.
|
26981542 |
2016 |
rs1036915
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Of the 12 common genetic variants examined, the rs1036915 (located in 3'UTR) and rs1187274 (located in intron-14), present in perfect linkage disequilibrium, exhibited an association (P = 0.017) with eGFR after accounting for the effects of age, sex, diabetes, diabetes duration, systolic blood pressure and blood pressure medication.
|
25885044 |
2015 |
rs1037733674
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients with diabetes and carriers of Gly40Ser showed basal C-peptide levels significantly lower than noncarriers (0.70 ng/mL versus 1.50 ng/mL, p = 0.008).
|
11961492 |
2002 |
rs10401969
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
rs1042488900
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No association with diabetes was showed in the meta-analyses of other six genetic variants, including SLC2A10 rs2335491, ATF6 rs2070150, KLF11 rs35927125, CASQ1 rs2275703, GNB3 C825T, and IL12B 1188A/C.
|
23922971 |
2013 |
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We analyzed the presence of SNP rs2228000 from XPC and rs1042522 from p53; and the relationship between risk factors such as smoking, alcohol intake, hypertension or diabetes.
|
27248495 |
2016 |
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Risk of cancer specific mortality, cardiovascular mortality, and respiratory mortality were not associated with Arg72Pro genotype overall; however, in exploratory subgroup analyses, genotype-associated risks of malignant melanoma and diabetes were altered.
|
28336930 |
2017 |
rs1042522
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The SNP rs4938723 and diabetes mellitus (DM) together were associated with an increased CRC risk, but the SNP TP53 Arg72Pro CC with DM showed a protective effect against CRC.
|
24337371 |
2014 |
rs1042615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1042615 T allele is associated with features resembling the phenotype of the V1aR(-/-) mouse, including uncoupling of the usual direct relation between glucose and triglycerides and an increased prevalence of diabetes in subjects with a high fat intake or who are overweight.
|
19056558 |
2009 |
rs1042713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
On the other hand, hypertensive cases, whether being isolated or associated with obesity and/or diabetes, showed a nonsignificant difference from controls in relation to all genotypic variants related to the ADRB2 G46A polymorphism (p>0.05).
|
22731644 |
2012 |
rs1042714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In both males and females, there were no differences in the indices of obesity, insulin resistance, and serum lipid levels between the subjects with and without the beta(2)-AR gene (Gln27Glu) variant in patients with normal glucose tolerance (NGT), impaired glucose tolerance (IGT), or diabetes (DM).
|
11288039 |
2001 |