rs2476601
|
|
|
1.000 |
GeneticVariation |
UNIPROT |
|
|
|
rs1307997067
|
|
G |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs137853236
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1555212014
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs28934906
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs397507478
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs587776825
|
|
GC |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs587780357
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs754729248
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs782511378
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
rs699
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We conclude that neither the M235T nor the T174M polymorphism in the angiotensinogen gene contributes to genetic susceptibility to diabetic nephropathy in white IDDM patients, whereas the TT genotype of the M235T is associated with elevated blood pressure in patients with diabetic nephropathy.
|
8593944 |
1996 |
rs4762
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No difference in distribution of T174M genotypes between nephropathic and normoalbuminuric IDDM patients was observed either: 148/44/1 (77/23/0.5%) vs. 141/42/2 (76/23/1%) had TT/TM/MM genotypes, respectively.
|
8593944 |
1996 |
rs699
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We conclude that the angiotensinogen polymorphism M235T might influence susceptibility to nephropathy in insulin-dependent diabetes, but its effect, if any, is rather small and independent of hypertension.
|
8621207 |
1996 |
rs699
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We have examined the angiotensin converting enzyme insertion/deletion polymorphism and angiotensinogen methionine 235 threonine polymorphism in a large cohort of Caucasian patients with IDDM and diabetic nephropathy.
|
8877296 |
1996 |
rs1267969615
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We have examined the angiotensin converting enzyme insertion/deletion polymorphism and angiotensinogen methionine 235 threonine polymorphism in a large cohort of Caucasian patients with IDDM and diabetic nephropathy.
|
8877296 |
1996 |
rs1801483
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Glucagon receptor Gly40Ser amino acid variant in Sardinian hypertensive non-insulin-dependent diabetic patients. Sardinian Diabetic Genetic Study Group (SDGSG).
|
9325468 |
1997 |
rs699
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In conclusion, results obtained in our family-based study support a role of the angiotensinogen gene M235T polymorphism, and specifically the T allele, in the development of diabetic nephropathy in IDDM.
|
9461232 |
1998 |
rs231775
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our data indicate that CTLA-4 exon 1 position 49 A/G dimorphism was significantly associated with predisposition to IDDM in our Central Poland population, particularly in patients lacking the strongly predisposing DRB1 alleles.
|
9690057 |
1998 |
rs17879469
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our data indicate that CTLA-4 exon 1 position 49 A/G dimorphism was significantly associated with predisposition to IDDM in our Central Poland population, particularly in patients lacking the strongly predisposing DRB1 alleles.
|
9690057 |
1998 |
rs5443
|
|
|
0.030 |
GeneticVariation |
BEFREE |
In conclusion we can find no evidence for the C825T polymorphism of the beta3 G-protein subunit as a major gene in the susceptibility to diabetic nephropathy in Type I diabetes.
|
9833937 |
1998 |
rs1801262
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Because the variant of the NeuroD/BETA2 gene (Ala45Thr) is associated with type 1 but not type 2 diabetes, it may be implicated in the loss of pancreatic beta-cells in type 1 diabetes.
|
10334323 |
1999 |
rs1258159645
|
|
|
0.010 |
GeneticVariation |
BEFREE |
By use of the transmission disequilibrium test (TDT), we analyzed the P187S polymorphism for association to type 1 diabetes in a population-based sample of 247 Danish nuclear type 1 diabetic families.
|
10447260 |
1999 |
rs1800566
|
|
|
0.010 |
GeneticVariation |
BEFREE |
By use of the transmission disequilibrium test (TDT), we analyzed the P187S polymorphism for association to type 1 diabetes in a population-based sample of 247 Danish nuclear type 1 diabetic families.
|
10447260 |
1999 |
rs2070600
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Human RAGE GLY82SER dimorphism and HLA class II DRB1-DQA1-DQB1 haplotypes in type 1 diabetes.
|
10553500 |
1999 |
rs1416580204
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Human RAGE GLY82SER dimorphism and HLA class II DRB1-DQA1-DQB1 haplotypes in type 1 diabetes.
|
10553500 |
1999 |