Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
1.000 GeneticVariation UNIPROT

dbSNP: rs1307997067
rs1307997067
TAX1BP3 ; P2RX5-TAX1BP3
G 0.700 GeneticVariation CLINVAR

dbSNP: rs137853236
rs137853236
HNF1A
T 0.700 CausalMutation CLINVAR

dbSNP: rs1555212014
rs1555212014
HNF1A
T 0.700 CausalMutation CLINVAR

dbSNP: rs28934906
rs28934906
MECP2
A 0.700 CausalMutation CLINVAR

dbSNP: rs397507478
rs397507478
BRAF
A 0.700 GeneticVariation CLINVAR

dbSNP: rs587776825
rs587776825
HNF1A
GC 0.700 CausalMutation CLINVAR

dbSNP: rs587780357
rs587780357
HNF1A
A 0.700 GeneticVariation CLINVAR

dbSNP: rs754729248
rs754729248
HNF1A
G 0.700 CausalMutation CLINVAR

dbSNP: rs782511378
rs782511378
FOXP3
A 0.700 GeneticVariation CLINVAR

dbSNP: rs699
rs699
AGT
0.080 GeneticVariation BEFREE We conclude that neither the M235T nor the T174M polymorphism in the angiotensinogen gene contributes to genetic susceptibility to diabetic nephropathy in white IDDM patients, whereas the TT genotype of the M235T is associated with elevated blood pressure in patients with diabetic nephropathy. 8593944

1996
dbSNP: rs699
rs699
AGT
0.080 GeneticVariation BEFREE We conclude that the angiotensinogen polymorphism M235T might influence susceptibility to nephropathy in insulin-dependent diabetes, but its effect, if any, is rather small and independent of hypertension. 8621207

1996
dbSNP: rs699
rs699
AGT
0.080 GeneticVariation BEFREE We have examined the angiotensin converting enzyme insertion/deletion polymorphism and angiotensinogen methionine 235 threonine polymorphism in a large cohort of Caucasian patients with IDDM and diabetic nephropathy. 8877296

1996
dbSNP: rs1267969615
rs1267969615
ACE
0.040 GeneticVariation BEFREE We have examined the angiotensin converting enzyme insertion/deletion polymorphism and angiotensinogen methionine 235 threonine polymorphism in a large cohort of Caucasian patients with IDDM and diabetic nephropathy. 8877296

1996
dbSNP: rs4762
rs4762
AGT
0.010 GeneticVariation BEFREE No difference in distribution of T174M genotypes between nephropathic and normoalbuminuric IDDM patients was observed either: 148/44/1 (77/23/0.5%) vs. 141/42/2 (76/23/1%) had TT/TM/MM genotypes, respectively. 8593944

1996
dbSNP: rs1801483
rs1801483
GCGR
0.010 GeneticVariation BEFREE Glucagon receptor Gly40Ser amino acid variant in Sardinian hypertensive non-insulin-dependent diabetic patients. Sardinian Diabetic Genetic Study Group (SDGSG). 9325468

1997
dbSNP: rs231775
rs231775
CTLA4
0.100 GeneticVariation BEFREE Our data indicate that CTLA-4 exon 1 position 49 A/G dimorphism was significantly associated with predisposition to IDDM in our Central Poland population, particularly in patients lacking the strongly predisposing DRB1 alleles. 9690057

1998
dbSNP: rs699
rs699
AGT
0.080 GeneticVariation BEFREE In conclusion, results obtained in our family-based study support a role of the angiotensinogen gene M235T polymorphism, and specifically the T allele, in the development of diabetic nephropathy in IDDM. 9461232

1998
dbSNP: rs17879469
rs17879469
HLA-DRB1
0.030 GeneticVariation BEFREE Our data indicate that CTLA-4 exon 1 position 49 A/G dimorphism was significantly associated with predisposition to IDDM in our Central Poland population, particularly in patients lacking the strongly predisposing DRB1 alleles. 9690057

1998
dbSNP: rs5443
rs5443
GNB3 ; CDCA3
0.030 GeneticVariation BEFREE In conclusion we can find no evidence for the C825T polymorphism of the beta3 G-protein subunit as a major gene in the susceptibility to diabetic nephropathy in Type I diabetes. 9833937

1998
dbSNP: rs231775
rs231775
CTLA4
0.100 GeneticVariation BEFREE There was no evidence that the CTLA-4 exon 1 polymorphism (49 A/G) confers genetic susceptibility to type 1 diabetes mellitus in our case-control study in Japanese subjects. 10619986

1999
dbSNP: rs1801262
rs1801262
NEUROD1 ; CERKL
0.090 GeneticVariation BEFREE Because the variant of the NeuroD/BETA2 gene (Ala45Thr) is associated with type 1 but not type 2 diabetes, it may be implicated in the loss of pancreatic beta-cells in type 1 diabetes. 10334323

1999
dbSNP: rs1801262
rs1801262
NEUROD1 ; CERKL
0.090 GeneticVariation BEFREE Recently, a significant association has been reported between NEUROD1-A45T polymorphism and Type 1 diabetes in the Japanese population. 10633878

1999
dbSNP: rs1217691063
rs1217691063
MTHFR
0.030 GeneticVariation BEFREE We analyzed the frequency of C677T MTHFR in IDDM and control groups. 10562465

1999
dbSNP: rs1167204443
rs1167204443
GAD1
0.020 GeneticVariation BEFREE There was no evidence that the CTLA-4 exon 1 polymorphism (49 A/G) confers genetic susceptibility to type 1 diabetes mellitus in our case-control study in Japanese subjects. 10619986

1999