Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE The rs4402960 polymorphisms were significantly associated with the T2DM risk after stratification by diagnostic criterion, size of sample and average age and BMI of cases, while there're no consistent results for rs1470579. 27294943

2016

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE We estimate that the rs13266634 single nucleotide polymorphism, a type 2 diabetes susceptibility genotype, has a genetic prevalence of 56.3%, 47.4% and 37.0% in Mexican Mestizo, Caucasian, and Asian populations. 25875676

2015

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE Our results suggest that rs13266634 may be an important genetic factor of type 2 diabetes risk among Asian and European but not African populations. 26214053

2015

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE SLC30A8 encodes a zinc transporter in the beta cell; individuals with a common missense variant (rs13266634; R325W) in SLC30A8 demonstrate a lower early insulin response to glucose and an increased risk of type 2 diabetes. 25348609

2015

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE Thus, we aimed to investigate the contribution of rs1111875 (HHEX), rs1800961 (HNF4α), rs5219 (KCNJ11), rs1801282 (PPARγ), rs10811661 (CDKN2A/2B), rs13266634 (SLC30A8), rs12779790 (CDC123/CAMK1D), rs7903146 (TCF7L2), rs9282541 (ABCA1) and rs13342692 (SLC16A11) polymorphisms in the genetic background of Maya population to associate their susceptibility to develop T2D. 25839936

2015

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE We found a lower risk of prediabetes and type 2 diabetes combined with coffee intake among individuals with the GT/TT of IGF2BP2 rs4402960, GG/GC of CDKAL1 rs7754840, or CC of KCNJ11 rs5215, which are known to be related to type 2 diabetes in East Asians. 25755232

2015

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE The present study confirms that the rs4402960 of IGF2BP2 gene is a strong candidate for Type 2 diabetes susceptibility and overweight/obesity risk in the Tunisian population. 24636221

2015

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE The variant rs13266634 in SLC30A8, encoding a β-cell-specific zinc transporter, is associated with type 2 diabetes. 24471563

2014

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE Our study suggested that the C allele of rs13266634 was associated with higher odds of T2D, and higher plasma zinc was associated with lower odds. 24306209

2014

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE Through sequencing or genotyping of ~150,000 individuals across 5 ancestry groups, we identified 12 rare protein-truncating variants in SLC30A8, which encodes an islet zinc transporter (ZnT8) and harbors a common variant (p.Trp325Arg) associated with T2D risk and glucose and proinsulin levels. 24584071

2014

dbSNP: rs13266634
rs13266634
C 1.000 GeneticVariation GWASCAT Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395

2014

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE We observed an association between allele variants of SLC30A8 [rs13266634 (C/T)] and type 2-diabetes (P = 0.04). 25501231

2014

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE Thus, the present study aimed to investigate the association between rs13266634 polymorphism and T2DM in Fars province, Southern Iran and compare the results with other populations. 24449369

2014

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE Gene-environment interaction analysis showed a significant interaction between rs13266634</span> in SLC30A8 gene and age on T2DM risk (P<0.0001). 24736664

2014

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE Using MGA, some common gene variants were found to have little (<5%) but significant impact on the heritability of T2D related QTs [KCNJ11 (rs5219), p=0.004]; [IGF2BP2 (rs4402960), p=0.02]; [SLC30A8 (rs13266634), p=0.05]; [CAPN10 (rs2975760), p=0.031]; [FTO (rs8050136), p=0.023]; [FTO (rs9939609), p=0.018] and [SLC30A8 (rs13266634), p=0.05]. 24993573

2014

dbSNP: rs13266634
rs13266634
C 1.000 GeneticVariation GWASDB Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395

2014

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE Five risk variants in IGF2BP2 (rs4402960, rs1470579), CDKAL1 (rs10946398), SLC30A8 (rs13266634), and HHEX (rs1111875) genes were nominally associated with T2DM in our samples. 24736664

2014

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE According to our results, the case-control study and meta-analysis revealed a significant association between the IGF2BP2 rs4402960 variant and type 2 diabetes in Moroccan and Arab populations. 24898818

2014

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE The present study provided data suggesting that the wild C allele of IGF2BP2 (rs4402960) had a protective effect against T2DM in obese subjects of Chinese Han population. 25062844

2014

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE The IGF2BP2 gene rs1470579 and rs4402960 polymorphisms were associated with T2DM and therapeutic efficacy of pioglitazone in this Chinese population. 25247335

2014

dbSNP: rs4402960
rs4402960
T 1.000 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

dbSNP: rs4402960
rs4402960
1.000 GeneticVariation BEFREE Using MGA, some common gene variants were found to have little (<5%) but significant impact on the heritability of T2D related QTs [KCNJ11 (rs5219), p=0.004]; [IGF2BP2 (rs4402960), p=0.02]; [SLC30A8 (rs13266634), p=0.05]; [CAPN10 (rs2975760), p=0.031]; [FTO (rs8050136), p=0.023]; [FTO (rs9939609), p=0.018] and [SLC30A8 (rs13266634), p=0.05]. 24993573

2014

dbSNP: rs4402960
rs4402960
T 1.000 GeneticVariation GWASDB Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation GWASDB Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India. 23300278

2013

dbSNP: rs13266634
rs13266634
1.000 GeneticVariation BEFREE We hypothesize that impaired function driven by rs13266634 increases T2D risk when combined with serum levels of nutrients. 23334806

2013