|
rs1800629
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study investigated the role of IL-1β-511 (rs16944), TLR4-896 (rs4986790) and TNF-α-308 (rs1800629) polymorphisms in type 2 diabetes mellitus (T2DM) among an endogamous Northern Indian population.
|
28620993 |
2017 |
|
rs1800630
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Therefore, this work was planned to evaluate the association of -863C/A (rs1800630) and -1031T/C (rs1799964) polymorphisms in TNF gene with plasma TNF-α levels and DN among subjects with type 2 diabetes (T2DM) in a population from North India.
|
25704106 |
2015 |
|
rs1800629
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A meta-analysis was applied to evaluate the associations between tumor necrosis factor-α (TNF-α) -308G>A (rs1800629) polymorphism and type 2 diabetes mellitus (T2DM).
|
23527193 |
2013 |
|
rs1800630
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This is the first report demonstrating association of rs1800630 and rs2229094 with type 2 diabetes in any population, suggesting an important role of the TNF-LTA locus in type 2 diabetes in North Indians.
|
20177654 |
2010 |
|
rs1799724
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a case-control study, the -238G>A (rs361525), -308G>A (rs1800629), and -857C>T (rs1799724) polymorphisms of the TNF gene were genotyped in 745 outpatients with type 2 diabetes, including 331 subjects without DR, 246 with nonproliferative DR (NPDR), and 168 with proliferative DR (PDR).
|
25634985 |
2015 |
|
rs1799964
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Therefore, this work was planned to evaluate the association of -863C/A (rs1800630) and -1031T/C (rs1799964) polymorphisms in TNF gene with plasma TNF-α levels and DN among subjects with type 2 diabetes (T2DM) in a population from North India.
|
25704106 |
2015 |
|
rs1800610
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six common genetic variants (rs2229094, rs1041981, rs1800630, rs1800629, rs361525, and rs1800610) in the TNF-LTA locus encoding the pro-inflammatory cytokines tumor necrosis factor-alpha (TNF-alpha) and lymphotoxin-alpha have been shown to be associated with various metabolic traits including susceptibility to type 2 diabetes, metabolic syndrome, insulin resistance, and increased body mass index (BMI) in Caucasians from different geographic locations and have yielded mixed results.
|
20177654 |
2010 |
|
rs361525
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Six common genetic variants (rs2229094, rs1041981, rs1800630, rs1800629, rs361525, and rs1800610) in the TNF-LTA locus encoding the pro-inflammatory cytokines tumor necrosis factor-alpha (TNF-alpha) and lymphotoxin-alpha have been shown to be associated with various metabolic traits including susceptibility to type 2 diabetes, metabolic syndrome, insulin resistance, and increased body mass index (BMI) in Caucasians from different geographic locations and have yielded mixed results.
|
20177654 |
2010 |
|
rs745738344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Relationship between polymorphisms 804C/A and 252A/G of lymphotoxin-alpha gene and -308G/A of tumor necrosis factor alpha gene and diabetic retinopathy in Japanese patients with type 2 diabetes mellitus.
|
16979413 |
2006 |