|
rs10019835
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
|
26305897 |
2015 |
|
rs10047560
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study for diabetic nephropathy genes in African Americans.
|
21150874 |
2011 |
|
rs10255208
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs741301-G allele and the rs10255208-GG genotype, gene-environment interaction between rs741301 and alcohol drinking were all associated with increased DN risk.
|
31798690 |
2019 |
|
rs1034589
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study for diabetic nephropathy genes in African Americans.
|
21150874 |
2011 |
|
rs1044498
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The potential association between the K121Q (A/C, rs1044498) polymorphism in the ectonucleotide pyrophosphatase/phosphodiesterase (ENPP1) gene and risk of diabetic kidney disease (DKD) has been investigated.
|
25794151 |
2015 |
|
rs1044498
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We confirmed the association between the rs1044498 SNP in ENPP1 and diabetic nephropathy, especially among obese diabetic patients, in the Taiwanese population.
|
21198320 |
2011 |
|
rs1049353
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The novel finding of our study is the association of the G1359A polymorphism with diabetic nephropathy and diabetic retinopathy in patients with T2DM.
|
24075694 |
2014 |
|
rs1056534
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found combined effect of TKT SNP rs11130362 and FN3K SNP rs1056534 on DN progression (p<0.01).
|
23492569 |
2014 |
|
rs1063537
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ADIPOQ genetic polymorphisms rs2241766 (+45T>G), rs1063537, rs2241767 and rs2082940 were correlated with the progression of DN in Taiwanese male patients with T2D.
|
24894086 |
2014 |
|
rs10770125
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IGF2 rs10770125 was also associated with DN in male T1D patients of the GoKinD population (P=0.038, OR=0.67 95% CI 0.46-0.98).
|
22770937 |
2013 |
|
rs10811661
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A SNP predisposing to type 2 diabetes mellitus, rs10811661 near CDKN2A/B, is associated with diabetic nephropathy in patients with type 1 diabetes mellitus.
|
22643932 |
2012 |
|
rs10823108
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, genetic variant rs10823108 in SIRT1 and variant rs17446614 in FoxO1 may contribute to the risk of DN in T2DM patients.
|
28860538 |
2017 |
|
rs10823108
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Mutation genotype GG and GG + AG in the rs10823108 locus can increase the risk of DKD.
|
30110438 |
2018 |
|
rs10868025
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.
|
19252134 |
2009 |
|
rs10951509
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The strongest associations in ELMO1 gene with DN occurred at rs741301 [odds ratio (OR) 1.89; p=0.004] and rs10951509 (OR 1.76; p=0.02).
|
22842811 |
2013 |
|
rs10952362
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
|
26305897 |
2015 |
|
rs11107616
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
|
26305897 |
2015 |
|
rs11130362
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found combined effect of TKT SNP rs11130362 and FN3K SNP rs1056534 on DN progression (p<0.01).
|
23492569 |
2014 |
|
rs1129456
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, the GREM1 variant rs1129456 associates with diabetic nephropathy, perhaps explaining some of the genetic susceptibility to this condition.
|
20150533 |
2010 |
|
rs1136410
|
|
|
0.010 |
GeneticVariation |
BEFREE |
eNOS 894G > T and PARP-1 Val762Ala polymorphisms appeared to associate significantly with DN, with the former contributing to an enhanced risk and the latter to a reduced susceptibility to DN in South Indian T2DM individuals.
|
25041504 |
2014 |
|
rs1137933
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These preliminary findings indicate that the NOS2 rs2779248, NOS2 rs1137933, and NOS3 rs3918188 genetic polymorphisms are potentially related to the susceptibility to T2DM, and the rs1800783 polymorphism might be considered as genetic risk factors for diabetic nephropathy, and family history of diabetes was closely associated with rs11771443 polymorphism in DN, and the genetic variants might be used as molecular markers for evaluating the risk of T2DM and diabetic nephropathy.© 2016 IUBMB Life, 68(7):516-525, 2016.
|
27192959 |
2016 |
|
rs1143770
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, let-7a-2 might participate in the regulation of the occurrence of DN, and a potential variant rs1143770 was significantly associated with the increased risk for DN.
|
23860321 |
2013 |
|
rs11538209
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that TGF-beta1 T29C polymorphism is not associated with the progression of diabetic nephropathy.
|
11576951 |
2001 |
|
rs11549465
|
|
|
0.030 |
GeneticVariation |
BEFREE |
HIF-1α Pro582Ser single nucleotide polymorphisms may be correlated with type 2 DN, which needs further exploration.
|
26600509 |
2015 |
|
rs11549465
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Recent work has shown that the <i>HIF-1A</i> Pro582Ser polymorphism is more resistant to hyperglycemia-mediated repression, thus protecting against the development of diabetic nephropathy.
|
31214621 |
2019 |