Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2294008
rs2294008
PSCA ; JRK
0.860 GeneticVariation BEFREE Cumulative evidence of an association was graded as strong for rs2294008 [odds ratio (OR) = 1.32, P = 5.1 × 10-33], rs2976392 (OR = 1.29, P = 1.8 × 10-8), rs9297976 (OR = 0.75, P = 1.4 × 10-7), rs2976391 (OR = 1.38, P = 6.1 × 10-5) and rs138377917 (OR = 0.53, P = 0.008) with gastric cancer, rs2294008 with bladder cancer (OR = 1.15, P = 8.0 × 10-19), gastritis (OR = 1.35, P = 1.2 × 10-5), duodenal ulcer (OR = 0.68, P = 2.4 × 10-57) and gastric ulcer (OR = 0.88, P = 1.7 × 10-7). 30407486

2019
dbSNP: rs2294008
rs2294008
PSCA ; JRK
0.860 GeneticVariation BEFREE Our study confirms an association between the PSCA rs2294008 C-allele and the risk of DU in a Japanese population. 31839644

2019
dbSNP: rs2294008
rs2294008
PSCA ; JRK
0.860 GeneticVariation BEFREE Recently, three genome-wide association studies have identified the PSCA (prostate stem cell antigen) rs2294008 polymorphism (C > T) associated with susceptibility to gastric cancer, bladder cancer, and duodenal ulcers, highlighting its critical role in disease pathogenesis. 27001215

2016
dbSNP: rs2294008
rs2294008
PSCA ; JRK
0.860 GeneticVariation BEFREE Frequency of PSCA rs2294008 C/C genotype in duodenal ulcer was 36.1%, which was significantly higher than those with gastric cancer (12.4%), gastric ulcer (19.0%), gastritis (10.7%), and H. pylori-negatives (19.5%) (p < .001). 25582162

2015
dbSNP: rs2294008
rs2294008
PSCA ; JRK
0.860 GeneticVariation BEFREE Genomic DNA from 603 Spanish patients with primary GC, 139 with DU and 675 healthy controls was typed for the PSCA rs2294008C>T polymorphism by PCR-TaqMan assays. 25721731

2015
dbSNP: rs2294008
rs2294008
PSCA ; JRK
0.860 GeneticVariation BEFREE From these results we conclude that the PSCA rs2294008 polymorphism is involved in the susceptibility to GC and DU, as well as in the prognosis of the diffuse-type of GC in Caucasians. 25721731

2015
dbSNP: rs2294008
rs2294008
PSCA ; JRK
0.860 GeneticVariation BEFREE The T allele of rs2294008 encodes a translation initiation codon upstream of the reported site and changes protein localization from the cytoplasm to the cell surface. rs505922 at ABO was also associated with duodenal ulcer in a recessive model (OR = 1.32; P = 1.15 × 10(-10)). 22387998

2012
dbSNP: rs2294008
rs2294008
PSCA ; JRK
C 0.860 GeneticVariation GWASCAT The T allele of rs2294008 encodes a translation initiation codon upstream of the reported site and changes protein localization from the cytoplasm to the cell surface. rs505922 at ABO was also associated with duodenal ulcer in a recessive model (OR = 1.32; P = 1.15 × 10(-10)). 22387998

2012
dbSNP: rs2294008
rs2294008
PSCA ; JRK
C 0.860 GeneticVariation GWASDB The T allele of rs2294008 encodes a translation initiation codon upstream of the reported site and changes protein localization from the cytoplasm to the cell surface. rs505922 at ABO was also associated with duodenal ulcer in a recessive model (OR = 1.32; P = 1.15 × 10(-10)). 22387998

2012
dbSNP: rs505922
rs505922
ABO
0.810 GeneticVariation BEFREE The T allele of rs2294008 encodes a translation initiation codon upstream of the reported site and changes protein localization from the cytoplasm to the cell surface. rs505922 at ABO was also associated with duodenal ulcer in a recessive model (OR = 1.32; P = 1.15 × 10(-10)). 22387998

2012
dbSNP: rs505922
rs505922
ABO
T 0.810 GeneticVariation GWASCAT The T allele of rs2294008 encodes a translation initiation codon upstream of the reported site and changes protein localization from the cytoplasm to the cell surface. rs505922 at ABO was also associated with duodenal ulcer in a recessive model (OR = 1.32; P = 1.15 × 10(-10)). 22387998

2012
dbSNP: rs505922
rs505922
ABO
T 0.810 GeneticVariation GWASDB The T allele of rs2294008 encodes a translation initiation codon upstream of the reported site and changes protein localization from the cytoplasm to the cell surface. rs505922 at ABO was also associated with duodenal ulcer in a recessive model (OR = 1.32; P = 1.15 × 10(-10)). 22387998

2012
dbSNP: rs10105842
rs10105842 		0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs1036385
rs1036385 		0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs1045574
rs1045574
PSCA
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs12155758
rs12155758 		0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs16896391
rs16896391
EYS
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs2164308
rs2164308
LY6K ; LNCOC1
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs2244163
rs2244163
LY6K ; LNCOC1
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs2572904
rs2572904
LNCOC1
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs2572925
rs2572925
LY6D
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs2585140
rs2585140
THEM6 ; LNCOC1
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs28473387
rs28473387 		0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs2920283
rs2920283
PSCA ; JRK
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012
dbSNP: rs2920297
rs2920297
PSCA ; JRK
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998

2012