This might constitute the first step towards identifying polymorphism combinations that predispose to endometriosis (IFNG (CA) repeat, GSTM1 null genotype, GSTP1 rs1695, WNT4 rs16826658 and WNT4 rs2235529) in a large cohort of patients with well-defined inclusion criteria.
The results demonstrated that WNT4 rs2235529 is associated with endometriosisin Chinese Han women, which may result in aberrant expression of WNT4, leading to the pathogenesis of endometriosis.