|
rs2306283
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our conclusion suggests that the interaction between the SLCO1B1 388A>G and 521T>C polymorphisms could be an important genetic determinant of hepatic function and the therapeutic efficiency of simvastatin in Chinese patients with hyperlipidemia.
|
30336686 |
2018 |
|
rs4149056
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our conclusion suggests that the interaction between the SLCO1B1 388A>G and 521T>C polymorphisms could be an important genetic determinant of hepatic function and the therapeutic efficiency of simvastatin in Chinese patients with hyperlipidemia.
|
30336686 |
2018 |
|
rs2306283
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The SLCO1B1 521T > C and 388A > G variants were found to be relatively common in Chinese patients with essential hyperlipidemia.
|
23263738 |
2013 |
|
rs4149056
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The SLCO1B1 521T > C and 388A > G variants were found to be relatively common in Chinese patients with essential hyperlipidemia.
|
23263738 |
2013 |
|
rs2306283
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The present study found that the allele frequencies of SLCO1B1 388A>G and 521T>C in Chinese patients with essential hyperlipidemia are comparable to those in healthy Chinese population.
|
20140004 |
2010 |
|
rs4149056
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The present study found that the allele frequencies of SLCO1B1 388A>G and 521T>C in Chinese patients with essential hyperlipidemia are comparable to those in healthy Chinese population.
|
20140004 |
2010 |
|
rs1800206
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate the individual or combined effects of PPARA-L162V, PPARG-C161T and APOE polymorphisms on hyperlipidemia in coronary heart disease (CHD) patients.
|
23583468 |
2013 |
|
rs4994
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To determine whether this SNP affects insulin resistance syndrome associated with type 2 diabetes, we examined its effects on susceptibility to obesity, hyperlipidemia and hypertension in type 2 diabetic subjects and on susceptibility to type 2 diabetes by interaction with other frequent genes involved in lipid metabolism, namely, beta3-adrenergic receptor (b3AR) Trp64Arg, phosphodiesterase 3B (PDE3B) c.1389G>A or lysosomal acid lipase (LAL) Thr-6Pro.
|
12965109 |
2003 |
|
rs1800206
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study examined the effect a polymorphism (L162V) in the gene for peroxisome proliferator activated receptor (PPAR) alpha in the development of non-insulin-dependent diabetes mellitus (type 2 DM), obesity and hyperlipidaemia.
|
11409711 |
2001 |
|
rs4994
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, no major difference was associated with the beta3AR Trp64Arg or FABP2 Ala54Thr polymorphism in terms of type 2 diabetes or hyperlipidemia in young to older Japanese men.
|
11699048 |
2001 |
|
rs10455872
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Topics enriched for CVD and hyperlipidemia had positive correlations with rs10455872 (P < 0.001), replicating a previous finding.
|
30759150 |
2019 |
|
rs1048943
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Hyperlipidemia could modulate the effect of CYP1A1 rs1048943 on the periodontal status of GAgP.
|
31032950 |
2019 |
|
rs2523608
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After stratification, hyperlipidemia remained a risk factor in women (OR = 4.735, 95% CI: 3.375⁻6.643) and men (OR = 3.640, 95% CI: 2.916⁻4.544) with rs2523608 GG genotype.
|
30934611 |
2019 |
|
rs4713518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study indicates that hyperlipidemia-sex interactions exist for gout risk in Taiwanese adults with rs2523608 GG and rs4713518 AA genotypes.
|
30934611 |
2019 |
|
rs498005
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Results:</b> C allele of rs498005 was significantly correlated with increased risk of AF (OR = 1.412, 95%CI = 1.012-1.970), and the association still exited after adjustment by age, gender, the status of smoking and drinking, histories of diabetes, hyperlipidaemia and myocardial infarction (adjusted OR = 1.473, 95%CI = 1.043-2.081).
|
31315459 |
2019 |
|
rs738409
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Accordingly, the naringenin-betaine cocrystals showed improved anti-hyperlipidemia effects on the C57 BL/6J PNPLA3 I148M transgenic mouse hyperlipidemia model.
|
30771018 |
2019 |
|
rs9349379
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Logistic regression analyses revealed that PHACTR1 rs9349379 GG genotype was significantly associated with increased risk of CAD in the recessive model (OR=2.359, 95% CI 1.442 to 3.862, p=0.001), even after adjusting for age gender, hypertension, type 2 diabetes, hyperlipidaemia and smoking habit.
|
30777881 |
2019 |
|
rs2066714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We conducted a cross-sectional study to investigate the effects of the adenosine triphosphate-binding cassette transporter 1 (ABCA1) I883M and lipoprotein lipase (LPL) HindIII polymorphisms on lipid levels in patients with hyperlipidemia.A total of 533 patients were enrolled.
|
28891316 |
2018 |
|
rs2302685
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It seems that LRP6 rs2302685 (V1062I) variant carriers are associated with an increased risk of hyperlipidemia in Iranian children and adolescents.
|
30039844 |
2018 |
|
rs662799
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Excess risk for low HDL-C and hyperlipidemia was associated with rs662799 genotype alleles of APOA5 SNPs in older Chinese adults.
|
29758349 |
2018 |
|
rs717620
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Female Chinese patients with hyperlipidemia carrying rs717620 GA/AA genotypes might have reduced benefit from simvastatin treatment.
|
30024814 |
2018 |
|
rs1042034
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The A allele of rs1042034 and the G allele of rs676210 may thus predispose middle-aged and elderly members of the Chinese Yugur population to HL in combination with other genetic or nutritional factors, and could be used as new genetic markers for HL screening.
|
28902930 |
2017 |
|
rs1137101
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Effects of LEP G2548A and LEPR Q223R Polymorphisms on Serum Lipids and Response to Simvastatin Treatment in Chinese Patients With Primary Hyperlipidemia.
|
26984935 |
2017 |
|
rs11615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Multiplicative interactions among SNP rs11615, alcohol drinking, history of T2DM, and history of hyperlipidemia could increase 5.06-fold risk of CAD (P = 1.59 × 10<sup>-9</sup>).
|
28743890 |
2017 |
|
rs1256046734
|
|
|
0.010 |
GeneticVariation |
BEFREE |
LEPR Q223R polymorphism, but not LEP G2548A, could modulate the efficacy of simvastatin in Chinese patients with primary hyperlipidemia.
|
26984935 |
2017 |