| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.010 | GeneticVariation | BEFREE | The aim of this study was to investigate the individual or combined effects of PPARA-L162V, PPARG-C161T and APOE polymorphisms on hyperlipidemia in coronary heart disease (CHD) patients. | 23583468 | 2013 |
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|
0.010 | GeneticVariation | BEFREE | A case of hyperlipidemia with homozygous apolipoprotein E5 (Glu3-->Lys). | 12069856 | 2002 |
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0.010 | GeneticVariation | BEFREE | Characterization of apolipoprotein E7 (Glu(244)-->Lys, Glu(245)--->Lys), a mutant apolipoprotein E associated with hyperlipidemia and atherosclerosis. | 9925654 | 1999 |
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|
0.010 | GeneticVariation | BEFREE | In relatives of the proband, APOE R112; R251G was consistently found in subjects with both hyperlipidemia and atherosclerosis. | 9360638 | 1997 |
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0.010 | GeneticVariation | BEFREE | Digestion with BbvI or Fnu4HI allows for rapid restriction isotyping for the rare apolipoprotein E R145C mutation associated with hyperlipidemia. | 7735921 | 1995 |
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|
0.010 | GeneticVariation | BEFREE | Digestion with BbvI or Fnu4HI allows for rapid restriction isotyping for the rare apolipoprotein E R145C mutation associated with hyperlipidemia. | 7735921 | 1995 |
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|
0.010 | GeneticVariation | BEFREE | This explains the significant effect of the apoE gene locus on the variability of plasma lipoprotein concentrations and moreover the implication of apoE alleles in the aetiology of multifactorial forms of hyperlipidaemia e.g. familial type III hyperlipidaemia (apoE2; arg158----cys) and polygenic hypercholesterolaemia (apoE4; cys112----arg). | 3141688 | 1988 |
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|
0.010 | GeneticVariation | BEFREE | This explains the significant effect of the apoE gene locus on the variability of plasma lipoprotein concentrations and moreover the implication of apoE alleles in the aetiology of multifactorial forms of hyperlipidaemia e.g. familial type III hyperlipidaemia (apoE2; arg158----cys) and polygenic hypercholesterolaemia (apoE4; cys112----arg). | 3141688 | 1988 |