In subgroup analysis according to ethnicity, a significant association was found between XRCC3 Thr241Met</span> (rs86</span>1539) polymorphism and leukemia risk in Asian but not in Caucasian or mixed populations.
The pooled OR showed that there was no statistically significant association between XRCC3 Thr241Met polymorphism and leukemia risk in overall including studies, while a risky association was observed for acute myeloid leukemia (AML) (dominant model TT/TC vs. CC: OR = 1.240, 95% CI = 1.018-1.511, P = 0.032).