Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1045642
rs1045642
0.060 GeneticVariation BEFREE In terms of infection incidence, polymorphism C3435T may contribute to potential life-threatening infections during paediatric ALL therapy, through glucocorticoid usage. 30508724

2019

dbSNP: rs1045642
rs1045642
0.060 GeneticVariation BEFREE This meta-analysis suggests there was no association between MDR1 C3435T polymorphism and children ALL risk in overall populations, but significant association with an increased risk in Asians. 25661341

2015

dbSNP: rs1045642
rs1045642
0.060 GeneticVariation BEFREE There were no association in distribution of genotypes of MDR-1 C3435T polymorphism and the risk of ALL. 23244145

2012

dbSNP: rs1045642
rs1045642
0.060 GeneticVariation BEFREE MDR1 C3435T polymorphism in Mexican children with acute lymphoblastic leukemia and in healthy individuals. 19317599

2008

dbSNP: rs1045642
rs1045642
0.060 GeneticVariation BEFREE To investigate their possible roles in disease susceptibility and some disease characteristics we genotyped C3435T and G2677T/A polymorphisms in multidrug resistance-1 (MDR1) gene with a single base extension method and the G34A and C421A polymorphisms of the breast cancer resistance protein gene with an allelic discrimination system in 396 children with acute lymphoblastic leukaemia (ALL) and 192 control patients. 18243305

2008

dbSNP: rs1045642
rs1045642
0.060 GeneticVariation BEFREE In conclusion, we do not have reason to assume that the C3435T SNP contributes to drug resistance of ALL and prognosis of ALL patients. 12851703

2003