Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913502
rs121913502
T 0.780 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121913502
rs121913502
A 0.780 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121913502
rs121913502
T 0.780 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

dbSNP: rs121913502
rs121913502
T 0.780 CausalMutation CLINVAR Molecular evaluation of DNMT3A and IDH1/2 gene mutation: frequency, distribution pattern and associations with additional molecular markers in normal karyotype Indian acute myeloid leukemia patients. 24606448

2014

dbSNP: rs121913502
rs121913502
T 0.780 CausalMutation CLINVAR Rapid detection of IDH2 (R140Q and R172K) mutations in acute myeloid leukemia. 23949315

2013

dbSNP: rs121913502
rs121913502
T 0.780 CausalMutation CLINVAR There were 9 AML patients with R140Q mutation, 1 patient with R140W mutation, and 1 patient with R172K mutation. 23815907

2013

dbSNP: rs121913502
rs121913502
T 0.780 CausalMutation CLINVAR Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. 23558173

2013

dbSNP: rs121913502
rs121913502
T 0.780 CausalMutation CLINVAR Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients. 22397365

2012

dbSNP: rs121913502
rs121913502
A 0.780 CausalMutation CLINVAR Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. 22417203

2012

dbSNP: rs121913502
rs121913502
A 0.780 CausalMutation CLINVAR Impact of genetic features on treatment decisions in AML. 22160010

2011

dbSNP: rs121913502
rs121913502
T 0.780 CausalMutation CLINVAR Impact of genetic features on treatment decisions in AML. 22160010

2011

dbSNP: rs121913502
rs121913502
T 0.780 CausalMutation CLINVAR Intriguingly, the IDH2 mutation p.R140Q and novel IDH1 mutation p.I99M co-occurred in a 75-year-old patient with AML developed from myelodysplastic syndromes (MDS). 20946881

2010

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121913503
rs121913503
A 0.720 CausalMutation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR Molecular evaluation of DNMT3A and IDH1/2 gene mutation: frequency, distribution pattern and associations with additional molecular markers in normal karyotype Indian acute myeloid leukemia patients. 24606448

2014

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR Rapid detection of IDH2 (R140Q and R172K) mutations in acute myeloid leukemia. 23949315

2013

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients. 22397365

2012

dbSNP: rs121913503
rs121913503
A 0.720 CausalMutation CLINVAR The role of mutations in epigenetic regulators in myeloid malignancies. 22898539

2012

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR Potential application of IDH1 and IDH2 mutations as prognostic indicators in non-promyelocytic acute myeloid leukemia: a meta-analysis. 22616558

2012

dbSNP: rs121913503
rs121913503
A 0.720 CausalMutation CLINVAR Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. 22417203

2012

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. 22417203

2012

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR Impact of genetic features on treatment decisions in AML. 22160010

2011

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR The prognostic significance of IDH2 mutations in AML depends on the location of the mutation. 21596855

2011

dbSNP: rs121913503
rs121913503
T 0.720 CausalMutation CLINVAR Evaluation of mutations in the isocitrate dehydrogenase genes in therapy-related and secondary acute myeloid leukaemia identifies a patient with clonal evolution to IDH2 R172K homozygosity due to uniparental disomy. 21250968

2011