| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
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0.850 | GeneticVariation | BEFREE | To assess if COPD-associated variants in 15q25.1 are methylation quantitative trait loci, epigenome-wide association analysis of four genetic variants, previously associated with COPD (P < 5 × 10<sup>-8</sup>) in the 15q25.1 locus (rs12914385:C>T-CHRNA3, rs8034191:T>C-HYKK, rs13180:C>T-IREB2 and rs8042238:C>T-IREB2), was performed in the Rotterdam study (n = 1489). | 29422661 | 2018 |
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0.850 | GeneticVariation | BEFREE | Our study showed the association of rs13180, rs16969968 and rs1051730 with COPD and lung function in Tatar population from Russia. | 28474623 | 2016 |
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0.850 | GeneticVariation | BEFREE | Our results support that IREB2 rs13180 is associated with COPD in Hainan population. | 25565795 | 2015 |
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0.850 | GeneticVariation | BEFREE | Four SNPs (rs1964678, rs12593229, rs965604 and rs13180) in IREB2 were associated with forced expiratory volume in 1 s (FEV(1))% predicted and three SNPs (rs16969968, rs8034191 and rs1051730) in CHRNA3/5 were both associated with FEV(1)% predicted and FEV(1)/FVC in COPD cases (P range 0.007-0.050). | 22914670 | 2012 |
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0.850 | GeneticVariation | BEFREE | We included three SNPs previously associated with COPD: rs7671167 (FAM13A), rs13180 (IREB2), and rs8034191 (CHRNA 3/5), and four SNPs associated with lung function in a genome-wide association study of general population samples: rs2070600 (AGER), rs11134242 (ADCY2), rs4316710 (THSD4), and rs17096090 (INTS12). | 22461431 | 2012 |
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0.850 | GeneticVariation | GWASDB | Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. | 21921092 | 2011 |
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0.850 | GeneticVariation | GWASCAT | Variants in FAM13A are associated with chronic obstructive pulmonary disease. | 20173748 | 2010 |
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0.850 | GeneticVariation | GWASDB | Variants in FAM13A are associated with chronic obstructive pulmonary disease. | 20173748 | 2010 |