|
rs10516487
|
|
|
0.880 |
GeneticVariation |
BEFREE |
In addition, we observed a genetic interaction between BLK (rs2736340T/C, rs13277113A/G) and BANK1 (R61H and A383T) associated with susceptibility to SLE.
|
31134304 |
2019 |
|
rs10516487
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Meta-analysis by autoimmune disease type revealed an association between both systemic lupus erythematosus and systemic sclerosis and the BANK1 rs10516487 T allele (OR = 1.294, 95% CI = 1.232-1.360, p<1.0 × 10-8, heterogeneity p = 0.556; OR = 1.102, 95% CI = 1.027-1.183, p = 0.017, heterogeneity p = 0.048).
|
28466820 |
2017 |
|
rs10516487
|
|
|
0.880 |
GeneticVariation |
BEFREE |
We confirmed the association of rs548234, rs2736340 and rs10516487 with SLE in Chinese Han and reinforced our hypothesis of their epistasis effect in regulating B-cell signaling in SLE.
|
26420661 |
2016 |
|
rs10516487
|
|
G |
0.880 |
GeneticVariation |
GWASCAT |
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
|
26502338 |
2015 |
|
rs10516487
|
|
|
0.880 |
GeneticVariation |
BEFREE |
We selected and identified three SNPs of BANK1 associated with SLE (rs17266594, P = 1.949e-10; OR = 1.380; 95% CI: 1.250-1.525; rs10516487, P = 2.642e-13; OR = 1.317; 95% CI: 1.223-1.417; rs3733197, P = 3.452e-06; OR = 1.193; 95% CI: 1.107-1.286); one SNP of TNFAIP3 associated with SLE (rs2230926, P = 1.502e-12; OR = 1.826; 95% CI: 1.545-2.157).
|
21208380 |
2011 |
|
rs10516487
|
|
|
0.880 |
GeneticVariation |
BEFREE |
This study implies that rs10516487 and rs17266594 polymorphisms might contribute to individual susceptibility to SLE and influence the ANA/SSA autoantibody response in SLE patients in Chinese population.
|
21078628 |
2011 |
|
rs10516487
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The strongest associations with SLE and BANK1 were at rs17266594 (corrected P-value=1.97 x 10(-5), odds ratio (OR)=1.22, 95% CI 1.12-1.34) and rs10516487 (corrected P-value=2.59 x 10(-5), OR=1.22, 95% CI 1.11-1.34).
|
19339986 |
2009 |
|
rs10516487
|
|
|
0.880 |
GeneticVariation |
BEFREE |
To investigate 1 functional (rs17266594) and 2 potentially functional (rs10516487 and rs3733197) BANK1 variants, which were previously identified as systemic lupus erythematosus (SLE) susceptibility markers, to test whether they are associated with rheumatoid arthritis (RA).
|
19180476 |
2009 |
|
rs10516487
|
|
|
0.880 |
GeneticVariation |
BEFREE |
In a genome-wide scan using 85,042 SNPs, we identified an association between SLE and a nonsynonymous substitution (rs10516487, R61H) in the B-cell scaffold protein with ankyrin repeats gene, BANK1.
|
18204447 |
2008 |
|
rs10516487
|
|
G |
0.880 |
GeneticVariation |
GWASCAT |
In a genome-wide scan using 85,042 SNPs, we identified an association between SLE and a nonsynonymous substitution (rs10516487, R61H) in the B-cell scaffold protein with ankyrin repeats gene, BANK1.
|
18204447 |
2008 |
|
rs10516487
|
|
G |
0.880 |
GeneticVariation |
GWASDB |
In a genome-wide scan using 85,042 SNPs, we identified an association between SLE and a nonsynonymous substitution (rs10516487, R61H) in the B-cell scaffold protein with ankyrin repeats gene, BANK1.
|
18204447 |
2008 |