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rs1057519781
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Activation of IGF-1R pathway and NPM-ALK G1269A mutation confer resistance to crizotinib treatment in NPM-ALK positive lymphoma.
|
31177400 |
2019 |
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rs121913503
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|
|
0.010 |
GeneticVariation |
BEFREE |
The test evaluates the expression of 20 genes, including 17 markers relevant to T-cell immunology and lymphoma biopathology, one EBV-related transcript, and variants of RHOA (G17V) and IDH2 (R172K/T).
|
31488561 |
2019 |
|
rs1353428252
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The test evaluates the expression of 20 genes, including 17 markers relevant to T-cell immunology and lymphoma biopathology, one EBV-related transcript, and variants of RHOA (G17V) and IDH2 (R172K/T).
|
31488561 |
2019 |
|
rs138228187
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TIRAP p.R81C is a novel lymphoma risk variant which enhances cell proliferation <i>via</i> NF-κB mediated signaling in B-cells.
|
30381301 |
2019 |
|
rs3099844
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>HCP5</i> rs3099844 was associated with anti-SSA (<i>P</i> = 0.006, OR = 3.07) and anti-SSB (<i>P</i> = 0.005, OR = 2.66) antibodies, severity of focus score (<i>P</i> = 0.03, OR = 12), and lymphoma development (<i>P</i> = 0.002, OR = 7.23).
|
30882006 |
2019 |
|
rs2231231
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Accordingly, we analyzed the association between a single-nucleotide polymorphism locus of aquaporin 3 (rs2231231) and Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (EBVaNPC), lymphoma (EBVaL), and gastric carcinoma in China.
|
30110699 |
2018 |
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rs2274084
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated GJB2 rs2274084 polymorphism in three types of tumors, including nasophoryngeal carcinoma (NPC), gastric cancer (GC) and lymphoma.
|
29103018 |
2018 |
|
rs1042752
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that rs1042752-located in the 3'-UTR of POU2AF1, which plays a vital role in lymphomagenesis-was significantly associated with lymphoma risk in a case-control study with 793 patients and 939 controls.
|
28345816 |
2017 |
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rs1946518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that IL-18 (rs1946518) and NFκB94 ins/del (rs28362491) contributed to lymphoma susceptibility and allele G in IL-18 was significantly associated with the risk of lymphoma.
|
29312552 |
2017 |
|
rs2071286
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The significant relationship between rs2071286 and rs9461776 MAF and the increased risk for NHL, suggests their use as non-invasive markers to categorize patients at risk of lymphoma.
|
29069725 |
2017 |
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rs28362491
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that IL-18 (rs1946518) and NFκB94 ins/del (rs28362491) contributed to lymphoma susceptibility and allele G in IL-18 was significantly associated with the risk of lymphoma.
|
29312552 |
2017 |
|
rs28934578
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We previously showed that the HSP90 inhibitor ganetespib potently suppresses T-lymphoma initiation and progression and extends overall survival (OS) in hotspot knockin mice expressing the p53 gain-of-function mutants R175H and R248Q (mutp53) by 30-59%.
|
28300840 |
2017 |
|
rs9461776
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The significant relationship between rs2071286 and rs9461776 MAF and the increased risk for NHL, suggests their use as non-invasive markers to categorize patients at risk of lymphoma.
|
29069725 |
2017 |
|
rs879253942
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The discovery of MYD88 L265P mutations in the vast majority of LPLs has had a major impact on the study of these lymphomas.
|
26454445 |
2016 |
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rs2395185
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We replicated a strong risk association in non-Hispanic White males with rs2395185, a protective marker for lymphoma.
|
24707947 |
2015 |
|
rs61756766
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Both the SS-lymphoma and SS-nonlymphoma patient subgroups exhibited significantly higher frequencies of the His159Tyr BAFF-R mutation compared to healthy controls (8.6% of SS-lymphoma patients and 6.2% of SS-nonlymphoma patients versus 1.7% of healthy controls; P = 0.02 and P = 0.04, respectively).
|
26097183 |
2015 |
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rs74790047
|
|
|
0.010 |
GeneticVariation |
BEFREE |
For individual cancer types, p.D140E was associated with lung cancer (adjusted OR, 3.99; 95% CI, 2.07-7.67; P < 0.001), malignant lymphoma (adjusted OR, 3.24; 95% CI, 1.43-7.33; P = 0.005), and rectum cancer (adjusted OR, 6.23; 95% CI, 2.31-16.8; P < 0.001).
|
25407497 |
2015 |
|
rs2227307
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In line with a previous study, rs2466571 in CD46 (HR = 0.73, 95% CI 0.58-0.91, p = 0.006) showed nominal association with lymphoma progression, as did two highly linked SNPs in IL8 (rs4073 HR = 0.78, 95% CI 0.62-0.97, p = 0.02; rs2227307 HR = 0.75, 95% CI 0.60-0.94, p = 0.01) previously associated with overall survival.
|
25294155 |
2014 |
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rs2466571
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In line with a previous study, rs2466571 in CD46 (HR = 0.73, 95% CI 0.58-0.91, p = 0.006) showed nominal association with lymphoma progression, as did two highly linked SNPs in IL8 (rs4073 HR = 0.78, 95% CI 0.62-0.97, p = 0.02; rs2227307 HR = 0.75, 95% CI 0.60-0.94, p = 0.01) previously associated with overall survival.
|
25294155 |
2014 |
|
rs4073
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In line with a previous study, rs2466571 in CD46 (HR = 0.73, 95% CI 0.58-0.91, p = 0.006) showed nominal association with lymphoma progression, as did two highly linked SNPs in IL8 (rs4073 HR = 0.78, 95% CI 0.62-0.97, p = 0.02; rs2227307 HR = 0.75, 95% CI 0.60-0.94, p = 0.01) previously associated with overall survival.
|
25294155 |
2014 |
|
rs867114783
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TP53(R167H/R167H) mutant pigs primarily developed lymphomas and osteogenic tumors, recapitulating the tumor types observed in mice and humans expressing orthologous TP53 mutant alleles.
|
25105366 |
2014 |
|
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Pooled results showed that the GSTT1 null polymorphism might increase the risk of lymphoma (odds ratio [OR] 2.26, 95% confidence interval [CI] 1.20, 4.24; p = 0.01; random-effects model), whereas the impact of GSTM1 and GSTP1 Ile105Val polymorphisms was not significant.
|
22734843 |
2013 |
|
rs17655
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the rs1800975, rs17655 and rs1805087 SNPs in DNA repair and synthesis of genes do not seem to play a major role in lymphoma susceptibility.
|
23818366 |
2013 |
|
rs1800975
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the rs1800975, rs17655 and rs1805087 SNPs in DNA repair and synthesis of genes do not seem to play a major role in lymphoma susceptibility.
|
23818366 |
2013 |
|
rs867329357
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Herein we performed a case-control study evaluating the influence of three single nucleotide polymorphisms (SNPs) in XPA, ERCC5 and MTR [rs1800975 (G-4A), rs17655 (Asp1104His) and rs1805087 (A2756G), respectively] in lymphoma risk.
|
23818366 |
2013 |