Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE In conclusion, we suggest that the XRCC1 gene Arg194Trp polymorphism is associated with gastric cancer susceptibility in the Chinese population. 27706710

2016

dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE This meta-analysis aimed to summarize published data about the association between two SNPs of XRCC1 (Arg194Trp and Arg399Gln) and treatment outcomes of patients with advanced gastric cancer. 24465544

2014

dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE However, significant associations between Arg194Trp polymorphism and gastric cancer were found in Asian. 25335737

2014

dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE Our findings demonstrated that the genetic variant Arg280His in XRCC1 may contribute to cancer progression and that XRCC1 Arg194Trp variants may act as a favorable prognostic indicator of resected GC, particularly among the diffuse-type GC. 23425027

2013

dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE In conclusion, XRCC1 Arg194Trp homozygous mutant genotype (Trp/Trp) was found to be associated with increased risk of GC. 21604176

2012

dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE In particular, individuals with the XRCC1 Arg194Trp variant genotype are at increased risk for GC below 60 years old. 23317230

2012

dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE ADPRT Val762Ala and XRCC1 Arg194Trp polymorphisms and risk of gastric cancer in Sichuan of China. 22901183

2012

dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), nucleotide excision repair (XPC-PAT, XPA-23G>A, ERCC1-19007T>C and XPD-L751Q), recombination (XRCC3-T241M) and alkylation damage reversal (MGMT-L84F) were tested for their potential role in the development of GC by using logistic regression models. 20817763

2010

dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group 1 (XRCC1, Arg194Trp and Arg399Gln), adenosine diphosphate ribosyl transferase (ADPRT, Val762Ala), 8-oxoguanine DNA glycosylase (OGG1, Ser326Cys) and apurinic/apyrimidinic endonuclease 1 (APE1, Asp148Glu) and evolution of H.pylori-associated precancerous gastric lesions, a population-based cohort study was conducted in Linqu County, a high-risk area of gastric cancer in China. 19147860

2009

dbSNP: rs1799782
rs1799782
0.100 GeneticVariation BEFREE To evaluate the association between polymorphisms XRCC1 Arg194Trp and Arg399Gln and XRCC3 Thr241Met and the risk for chronic gastritis and gastric cancer, in a Southeastern Brazilian population. 16425350

2005