Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.850 | GeneticVariation | BEFREE | The single nucleotide polymorphism (SNP) rs17824933 in the CD6 gene has been identified and validated as a genetic risk factor for the development of MS. | 26844569 | 2016 |
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0.850 | GeneticVariation | BEFREE | CD6 has recently been identified and validated as risk gene for multiple sclerosis (MS), based on the association of a single nucleotide polymorphism (SNP), rs17824933, located in intron 1. | 23638056 | 2013 |
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0.850 | GeneticVariation | BEFREE | In the recently published meta-analysis of multiple sclerosis genome-wide association studies De Jager et al. identified three single nucleotide polymorphisms associated to MS: rs17824933 (CD6), rs1800693 (TNFRSF1A) and rs17445836 (61.5 kb from IRF8). | 21552549 | 2011 |
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0.850 | GeneticVariation | BEFREE | Our recent meta-analysis of genome-wide association studies of multiple sclerosis (MS) identified a new susceptibility locus tagged by a single nucleotide polymorphism, rs17824933 (p = 3.8 × 10(-9)), that is found in a block of linkage disequilibrium containing the CD6 gene. | 21849685 | 2011 |
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0.850 | GeneticVariation | GWASDB | Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. | 21833088 | 2011 |
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0.850 | GeneticVariation | BEFREE | We also found convincing evidence for allelic imbalance at multiple reporter exonic SNPs in CD6 for two samples heterozygous at the multiple sclerosis-associated variant rs17824933, linking GWA findings with variation in gene expression. | 19825846 | 2010 |
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G | 0.850 | GeneticVariation | GWASCAT | Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. | 19525953 | 2009 |
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G | 0.850 | GeneticVariation | GWASDB | Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. | 19525953 | 2009 |