Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.820 | GeneticVariation | BEFREE | The goal of the current study was to investigate the association of single nucleotide polymorphisms (SNP) with the immunologically related genes responsible for the disease, composed of CD58 (rs2300747 A>G), CD226 (rs763361 C>T), and HLA-G (rs1611715 A>C), with MS susceptibility. | 30128676 | 2018 |
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|
0.820 | GeneticVariation | GWASCAT | Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. | 27386562 | 2016 |
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|
0.820 | GeneticVariation | GWASDB | Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. | 21833088 | 2011 |
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|
A | 0.820 | GeneticVariation | GWASCAT | Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. | 22190364 | 2011 |
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|
A | 0.820 | GeneticVariation | GWASDB | Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. | 22190364 | 2011 |
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|
A | 0.820 | GeneticVariation | GWASCAT | Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. | 19525953 | 2009 |
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|
0.820 | GeneticVariation | BEFREE | This protective rs2300747(G) allele is associated with a dose-dependent increase in CD58 mRNA expression in lymphoblastic cell lines (P = 1.1 x 10(-10)) and in peripheral blood mononuclear cells from MS </span>subjects (P = 0.0037). | 19237575 | 2009 |
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|
A | 0.820 | GeneticVariation | GWASDB | Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. | 19525953 | 2009 |