|
rs11554825
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We noticed an association between obesity and variations in TGR5 rs11554825 SNP.
|
31812910 |
2020 |
|
rs1333048
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The findings indicate that there are significant associations between AA genotype of rs1333048 SNP and general and central obesity, and significant interaction between alleles of this SNP and major dietary patterns on the odds of general obesity, BFP, waist circumference, BMI, WHtR and hs-Crp.
|
30600348 |
2020 |
|
rs3847987
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Allele C of rs3847987 was risk factors for obesity (P = 0.006).
|
31813936 |
2020 |
|
rs10246939
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, <i>TAS2R38</i> rs10246939 variation was associated with Koreans' dietary intake and increased their risk of obesity.
|
31438650 |
2019 |
|
rs10891319
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, rs11205591 and rs10891319 polymorphisms showed an additive interaction with BMI and obesity risk.
|
30782949 |
2019 |
|
rs1109859
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One hundred ninety-six children with obesity (101 females, 95 males) were evaluated using anthropometric measurements, dietary intakes, plasma and RBC PUFA quantification, blood biochemistry, and 55 single nucleotide polymorphisms within 14 genes. phosphatidylethanolamine <i>N</i>-methyltransferase (<i>PEMT</i>) rs1109859 and methylenetetrahydrofolate reductase gene (<i>MTHFR</i>) rs4846052 genotypes were associated with PUFA levels in RBCs.
|
31671528 |
2019 |
|
rs11205591
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, rs11205591 and rs10891319 polymorphisms showed an additive interaction with BMI and obesity risk.
|
30782949 |
2019 |
|
rs11665896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results The T allele of rs11665896 in the FGF21 gene was associated with obesity (odds ratio [OR] = 1.99, 95% confidence interval [CI] = 1.14-3.46; p = 0.0151).
|
31323006 |
2019 |
|
rs12152703
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The G-allele frequency of <i>KLB</i> rs7674434 and T-allele frequency of rs12152703 were higher in the obese with NAFLD than obese without NAFLD group (<i>P</i> = 0.004 and <i>P</i> = 0.006), but the genotype distribution between two non-obese groups did not differ.
|
31548436 |
2019 |
|
rs1275489527
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we report the first Saudi female patient with mild to moderate ID, early onset of obesity and speech delay associated with a de novo pathogenic SNV in the MYT1L gene (c. 1585G>A [Gly529Arg]), which causes an amino acid change from Gly to Arg at position 529 that leads to mental retardation, autosomal dominant 39.
|
30796847 |
2019 |
|
rs13188458
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification analyses by body mass index, exercise, and dietary fat intake with combined phenotypes showed that genetically elevated IR was associated with greater breast cancer risk in overall obesity and inactive subgroups (single contributor: MTRR/LOC729506 rs13188458; HR = 2.21, 95% CI: 1.03-4.75).
|
31246991 |
2019 |
|
rs13334070
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The joint model showed that rs13334070, in the intron 4 of the RPGRIP1L gene, has a significant association with obesity.
|
30597647 |
2019 |
|
rs1360780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association of rs1360780 with obesity and metabolic characteristics in 250 obese children and adolescents (mean age 12.3±3.6years, BMI ≥95th percentile).
|
28007534 |
2019 |
|
rs1642785
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We have selected three <i>p53</i> polymorphisms, rs1642785 (C > G), and rs9894946 (A > G), and rs1042522 (Pro72Arg; C > G) and assessed their association with obesity risk in the Saudi population.
|
31762593 |
2019 |
|
rs1800797
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Minor alleles of rs1800795 raised and rs1800797 reduced the risk of obesity, while rs1800796 and rs2069845 may not be associated.
|
31472475 |
2019 |
|
rs1803274
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study investigated the association of three single nucleotide polymorphisms (SNPs) in the BCHE gene: -116G > A (rs1126680), 1615GA (rs1803274), 1914A < G (rs3495), with obesity and lipid metabolism markers, body mass index (BMI), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglyceride (TG) levels, and BChE enzymatic activity in obese (BMI≥30/n = 226) and non-obese women (BMI < 25/n = 81).
|
28497838 |
2019 |
|
rs2069849
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggested that the C allele of rs1800796 and the C allele of rs2069849 of IL-6 gene interaction between rs1800796 and abdominal obesity were all associated with increased OST risk.
|
31301734 |
2019 |
|
rs2075654
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs2075654 polymorphism of DRD2 is related to long-term obesity alleviation in obese Chinese children and adolescents.
|
30269448 |
2019 |
|
rs2231142
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No significant interaction between SLC2A9 rs7678287 and ABCG2 rs2231142 genotypes and obesity was observed.
|
30305239 |
2019 |
|
rs223828
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNPs rs223828 in CCL17 and rs6749704 in CCL20 were correlated with obesity as estimated by BMI (p = 0.0004, p = 0.029, respectively).
|
30536157 |
2019 |
|
rs2331841
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The obesity risk of subjects with the AG genot</span>ype in the rs2331841 site was 82% higher than the risk of those with the GG genotype (<i>β</i> = 0.60, OR = 1.82, <i>P</i>=0.030).
|
31781208 |
2019 |
|
rs2388405
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An unweighted genetic risk score (GRS) was calculated for two <i>FTO</i> single-nucleotide polymorphisms (rs8050136 and rs2388405) by summation of the number of risk alleles for obesity.
|
31516636 |
2019 |
|
rs2441666
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only FTO rs9939609 A>T polymorphism was associated with obesity and no association was observed with ADIPOQ rs2441666 G>T and ACE rs4340288 DIP.
|
30416093 |
2019 |
|
rs2721
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Subjects with GT/TT genotype or T allele of rs2721 and GT genotype of rs9719268 were associated with an increased risk of obesity.
|
31658356 |
2019 |
|
rs2784243
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In further analyses, we detected a novel obesity and BMI-associated locus at PKHD1 (rs2784243, obese vs. thin p = 5.99x10-6, obese vs. controls p = 2.13x10-6 pBMI = 2.3x10-13), associations at loci recently discovered with much larger sample sizes (e.g.
|
30677029 |
2019 |