Variant Gene Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11540654
rs11540654
0.020 GeneticVariation BEFREE Cumulative risk analysis revealed 3 unfavorable variants that increased significantly the risk of developing ovarian cancer (p.Ile1145 = ABCB1+ p.Asp1853Asn ATM+ p.Ser406Ala ATP7B- OR 7,47; p = 0,002) and significantly modified the progression free survival (PFS) of the patients, and also two favorable genotypes which protected against ovarian cancer (p.Arg952Lys ATP7B+ p.Arg72Pro TP53- OR 0,50; p = 0,008). 25591549

2016

dbSNP: rs397516436
rs397516436
0.020 GeneticVariation BEFREE The primary breast cancer displayed a TP53 frameshift (p.Q317fs) mutation, whereas and the adnexal lesion harbored a TP53 nonsense (p.R213*) mutation, consistent with a diagnosis of two independent primary tumors (i.e. breast and ovarian cancer). 24220311

2014

dbSNP: rs11540654
rs11540654
0.020 GeneticVariation BEFREE Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma. 15221786

2004

dbSNP: rs397516436
rs397516436
0.020 GeneticVariation BEFREE High prevalence of codon 213Arg-->Stop mutations of the TP53 gene in human ovarian cancer in the southwestern part of The Netherlands. 9579562

1998

dbSNP: rs587781858
rs587781858
0.010 GeneticVariation BEFREE Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma. 15221786

2004

dbSNP: rs672601296
rs672601296
0.010 GeneticVariation BEFREE The microsomal epoxide hydrolase Tyr113His polymorphism: association with risk of ovarian cancer. 11255266

2001